Table 2

Overall SVR according to different variables
Variable N° of pts/Tot pts SVR (%) P value
Sex
F 68/145 46 ns
M 119/243 49
Age
< 50 123/210 58 0.00001
> 50 64/178 37
BMI
< 25 145/280 51 0.05
> 25 32/82 39
ALT
< 100 139/261 53 0.002
> 100 51/127 40
HCV-RNA
≤ 5 .60 log10 64/96 66 0.00004
> 5 .60 log10 123/292 42
Genotype
1a 91/165 55 0.02
1b 96/223 43
Staging*
≤ S3 142/262 54 0.00008
> S3 15/60 25
Drug
PegINF α 2b 100/195 51 ns
PegINF α 2a 87/193 45
RVR
Yes 129/160 80 0.000001
No 58/228 25

Legend. SVR: sustained virological response, F: female, M:male, PegINF: pegylated interferon, BMI: body mass index, ALT: alanine aminotransferase value (IU/ml); RVR: rapid virological response.

*322 over 388 patients were submitted to liver biopsy and analyzed for this variable.

Pellicelli et al.

Pellicelli et al. BMC Gastroenterology 2012 12:162   doi:10.1186/1471-230X-12-162

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