Table 4

Proportion of immune-mediated diseases and time development in relation to celiac disease (CD) diagnosis
All Males Females pa Before Jointlyb After nc pd
Diabetes, insulin n 39 24 15 0.19 53% 6% 41% 32 0.29
% 3.8 4.8 2.8
Diabetes, non-insulin n 24 17 7 0.04 20% 13% 67% 15 0.20
% 2.3 3.4 1.3
Rheumatic disease n 80 19 61 <0.01 42% 8% 50% 48 1.00
% 7.8 3.8 11
Thyroid disease n 94 19 75 <0.01 47% 15% 38% 68 0.05e
% 9.1 3.8 14
Vitiligo n 39 16 23 0.24 72% 11% 17% 18 <0.01
% 3.8 3.2 4.3
Alopecia areata n 19 11 8 0.52 62% 8% 31% 13 0.16
% 1.8 2.2 1.5
Inflammatory bowel disease n 44 17 27 0.09 31% 27% 42% 26 0.43
% 4.3 3.4 5.0
Any immune-mediated diseasee n 256 170 86 <0.01 n/af n/a n/a n/a n/a
% 25 32 17

a Comparing males with females using Students t-test.

b CD associated immune-mediated disease reported for same year as CD diagnosis.

c Specified year for both CD and other diagnosis.

d Comparing proportion with auto-immune disease diagnosed before or jointly with CD with proportion after CD diagnosis.

e Non-significant.

f Not including non-insulin dependent diabetes.

g Comparisons not applicable for “Any disease”.

Norström et al.

Norström et al. BMC Gastroenterology 2012 12:125   doi:10.1186/1471-230X-12-125

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