Table 2

Distribution of each variable according to fibrosis stages

Factor

F0 (n = 29)

F1(n = 39)

F2(n = 34)

F3(n = 34)

F4(n = 21)

P value


Age

25.9 ± 2.4

37.9 ± 9.5

42.8 ± 7.6

37.7 ± 8.5

48.4 ± 7.1

< 0.05

Sex (M/F)

19/10

35/4

26/8

20/14

14/7

0.247

Genotype (1a/3a)

8/21

4/35

3/31

3/31

4/17

0.258

HAI score

3.8 ± 2.1

6.05 ± 2.8

6.8 ± 3.2

6.9 ± 4.02

7.6 ± 2.9

< 0.05

Viral load

6.2 × 105 ± 1.2 × 106

1.3 ± × 107 ± 1.5 × 107

2.1 × 108 ± 2.4 × 108

2.4 × 107 ± 2.5 × 107

2.9 × 105 ± 2.9 × 105

< 0.05

Hb level

12.8 ± 1.3

12.6 ± 1.2

12.77 ± 1.7

12.9 ± 1.3

12.3 ± 1.2

0.328

Bilirubin

0.7 ± 0.1

0.88 ± 0.2

0.99 ± 0.27

1.2 ± 0.3

1.62 ± 0.31

< 0.05

ALT

120.2 ± 71.9

117.8 ± 55.3

152.1 ± 66.5

139.6 ± 56.6

147.5 ± 61.2

0.091

ALP

72.6 ± 16.8

88.1 ± 47.5

110.7 ± 45.1

208.6 ± 75.9

323.8 ± 80.1

< 0.05

AST

83.1 ± 57.9

107.1 ± 66.5

95.9 ± 51.4

106.9 ± 65.4

155.5 ± 90.6

< 0.05

Albumin

4.5 ± 0.1

4.3 ± 0.16

4.2 ± 0.18

4.08 ± 0.2

3.6 ± 0.33

< 0.05

Platelet count

191.3 ± 18.7

185.1 ± 21.2

162.1 ± 16.6

125.5 ± 18.7

81.6 ± 17.7

< 0.05

AAR

0.8 ± 0.58

1.14 ± 1.21

0.93 ± 1.1

1.02 ± 1.03

1.26 ± 0.95

0.522

APRI

1.04 ± 0.75

1.39 ± 0.87

1.40 ± 0.75

2.09 ± 1.33

4.7 ± 3.1

< 0.05

FI

1.24 ± 0.26

1.51 ± 0.28

1.81 ± 0.27

2.33 ± 0.28

3.2 ± 0.4

< 0.05

FIB-4

1.21 ± 0.95

2.17 ± 1.47

2.31 ± 1.57

3.06 ± 2.1

8.73 ± 6.59

< 0.05


Ahmad et al. BMC Gastroenterology 2011 11:44   doi:10.1186/1471-230X-11-44

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