Relationship between FASN concentration and liver disease. Correlation between serum FASN concentration and alanine aminotransferase activity both in non-HCV co-infected (A) and HCV co-infected (B) HIV-infected patients. Analyses for the discrimination of HCV co-infected patients using the receiver-operating curves (C) for serum (1) alanine aminotransferase activity, (2) aspartate aminotransferase activity, (3) FASN concentration, and (4) MCP-1 concentrations showed that the relative contributions of FASN and MCP-1 were significant but negligible. The area under the curve values (95% CI), were respectively: 0.834 (0.764-0.904), 0.754 (0673-0.835), 0.713 (0.626-0.801) and 0.652 (0.560-0.744).
Aragonès et al. BMC Gastroenterology 2010 10:92 doi:10.1186/1471-230X-10-92