Table 2

Sensitivity, specificity, and percentage of correct classification of individuals with and without cognitive impairment and those with AD and without cognitive impairment for different cut-off scores of the crude MMSE scores obtained by GPs and by UVAs; Rome, Italy, 2005



Crude MMSE obtained by GPs
Crude MMSE obtained by UVAs


MMSE cut-off score
Sensitivity
Specificity
% correctly classified
PPV
NPV
Sensitivity
Specificity
% correctly classified
PPV
NPV

Classification of individuals with and without cognitive impairment
16
58.8%
85.7%
65.9%
92.0%
41.1%
53.7%
94.1%
64.4%
96.2%
42.3%

17
63.1%
82.1%
68.1%
90.7%
42.9%
55.8%
91.7%
65.3%
94.9%
42.8%

18
66.5%
77.4%
69.4%
89.1%
44.5%
60.1%
91.7%
68.5%
95.2%
45.3%

19
75.1%
69.1%
73.5%
87.1%
45.5%
64.8%
89.3%
71.3%
94.4%
47.8%

20
83.7%
64.3%
78.6%
86.7%
50.0%
70.8%
88.1%
75.4%
94.3%
52.1%

21
88.8%
53.6%
79.5%
84.2%
58.7%
75.1%
85.7%
77.9%
93.6%
55.4%

22
92.7%
39.3%
78.6%
80.9%
63.4%
79.4%
79.8%
79.5%
91.6%
58.3%

23
95.7%
21.4%
76.0%
77.2%
66.0%
83.3%
77.4%
81.7%
91.1%
62.5%

24
98.7%
4.8%
73.8%
74.2%
64.3%
87.1%
72.6%
83.3%
89.8%
67.0%

25
99.6%
0.0%
73.2%
73.4%
57.1%
91.9%
64.3%
84.5%
87.7%
74.0%

26
100.0%
0.0%
73.5%
73.5%
0.0%
94.9%
59.5%
85.5%
86.7%
80.7%

Classification of individuals with AD and without cognitive impairment
16
71.6%
90.5%
80.5%
89.5%
73.8%
71.6%
94.1%
82.1%
93.2%
74.5%

17
75.8%
85.7%
80.5%
85.7%
75.8%
73.7%
91.7%
82.1%
90.9%
75.5%

18
81.1%
82.1%
81.6%
83.7%
79.3%
75.8%
91.7%
83.2%
91.1%
77.0%

19
83.2%
77.4%
80.5%
80.6%
80.2%
80.0%
89.3%
84.4%
89.4%
79.8%

20
90.5%
69.1%
80.5%
76.8%
86.6%
88.4%
88.1%
88.3%
89.4%
87.1%

21
96.8%
64.3%
81.6%
75.4%
94.7%
91.6%
85.7%
88.8%
87.9%
90.0%

22
96.8%
53.6%
76.5%
70.2%
93.8%
92.6%
79.8%
86.6%
83.8%
90.5%

23
96.8%
39.3%
69.8%
64.3%
91.7%
94.7%
77.4%
86.6%
82.6%
92.9%

24
97.9%
21.4%
62.0%
58.5%
90.0%
94.7%
72.6%
84.4%
79.7%
92.4%

25
99.0%
4.8%
54.8%
54.0%
80.0%
97.9%
64.3%
82.1%
75.6%
96.4%

26
99.0%
0.0%
52.5%
52.8%
0.0%
97.9%
59.5%
79.9%
73.2%
96.2%

Note: Individuals whose score was equal to or lower than the reported cut-off value were classified as having cognitive impairment in the first section of the table and as having AD in the second section of the table.

Pezzotti et al. BMC Family Practice 2008 9:29   doi:10.1186/1471-2296-9-29