Table 2 |
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|
Baseline characteristics of study participants |
||
|
Oral B12 (N = 26) |
Placebo (N = 24) |
|
|
|
||
|
Gender (Female) |
14 (53.8%) |
13 (54.2%) |
|
n (%) |
||
|
Age |
||
|
Mean (SD) |
69.6 yrs (SD = 18.8) |
68.6 yrs (SD = 18.5) |
|
Median (range) |
76 yrs (31 - 91) |
75 yrs (18 - 88) |
|
Serum B12 |
||
|
Mean (SD) |
164 pM/l (SD = 24) |
154 pM/l (SD = 20) |
|
Median (range) |
164 pM/l (127 - 203) |
150 pM/l (126 - 191) |
|
Serum MMA |
||
|
Mean (SD) |
0.43 μmol/l (SD = 0.25)* |
0.41 μmol/l (SD = 0.24)* |
|
Median (range) |
0.32 μmol/l (0.19 - 1.1) |
0.31 μmol/l (0.15 - 0.92) |
|
MMA ≥ 0.26 μmol/l |
||
|
n (%) |
18 (83.3%)* |
16 (72.7%)* |
|
Serum HCys |
||
|
Mean (SD) |
18.3 μmol/l (SD = 6.6)* |
15.0 μmol/l (SD = 5.3)* |
|
Median (range) |
18.1 μmol/l (9.8 - 31.5) |
14.3 μmol/l (7.5 - 27.1) |
|
Hematocrit |
||
|
Mean (SD) |
40.3% (SD = 4.2)† |
39.5% (SD = 4.6) |
|
Median (range) |
39.5% (32 - 46) |
40% (27 - 47) |
|
Mean corpuscular volume |
||
|
Mean (SD) |
91.2 fl (SD = 9.2)† |
92.6 fl (SD = 5.1) |
|
Median (range) |
90 fl (63 - 100) |
92 fl (81 - 111) |
|
Serum creatinine |
||
|
Mean (SD) |
96.4 μmol/l (SD = 27.9) |
89.0 μmol/l (SD = 27.2) |
|
Median (range) |
86 μmol/l (60 - 160) |
89 μmol/l (37 - 137) |
|
Serum folic acid |
||
|
Mean (SD) |
16.6 nmol/l (SD = 9.1) |
19.2 nmol/l (SD = 10.9) |
|
Median (range) |
16.2 nmol/l (5.6 - 45.3) |
14 nmol/l (5.4 - 33) |
|
|
||
|
Hcys = homocysteine, MMA = methylmalonic acid, SD = standard deviation * Transport inconvenient generated missing total at random data; samples were not analysed for 2 patients in the oral B12 group and for 2 patients in the placebo group. † One physician did not report results from the blood formula onto the case report form. Data were unvailable for one patient in the oral B12 group. |
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|
Favrat et al. BMC Family Practice 2011 12:2 doi:10.1186/1471-2296-12-2 |
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