Additional file 1.

Joint analysis with the first-order Markov assumption: relation of age to ARM transition probabilities for different birth cohorts. Clockwise from top left, panels describe incidence, progression, disappearance and regression probabilities. In each panel, black lines are based on observed data, red lines are fitted from the models (11, 12) for separate analysis, green lines are from the joint analysis models (13, 14) under the first-order Markov assumption, and purple lines are from the joint analysis models (13, 14, 15) without the first-order Markov assumption. Also, in each panel, the different numbers represent different birth cohorts (birth years).

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Huang BMC Medical Research Methodology 2008 8:40   doi:10.1186/1471-2288-8-40