Table 4

Search results for randomised controlled trials on negative pressure wound therapy* (Status: December 2006)
Study status
 No.
 Abstract
 Information source for abstract
 Sponsor (ID†)
 Reply to inquiry to sponsor or author
 Patients planned‡
 Patients analysed§
 Results data available
 Full-text publication available||
Completed









1
 Vuerstaek [74]
 WUWHS 2004
 KCI (VAC VLU)
 KCI
 -
 60
 Yes
 Vuerstaek 2006 [23]

2
 No abstract
 -
 Unclear
 -
 -
 60
 Yes
 Llanos 2006 [25]

3
 Obdeijn [75]
 WUWHS 2004
 KCI (No ID)
 KCI
 -
 65
 Yes
 Braakenburg 2006 [21]

4
 Payne [76]
 WUWHS 2004
 KCI (VAC 2001–07)
 KCI; author
 -
 162
 Yes#
 Armstrong 2005 [22]

5
 Moues [77]
 WUWHS 2004
 KCI (PMID 14974959)
 KCI
 -
 54
 Yes#
 Moues 2004 [20]

6
 Heath [78]
 The Cochrane Library
 KCI (PMID 15468399)
 KCI; author
 -
 20
 Yes#
 Moisidis 2004 [18]

7
 No abstract
 -
 KCI (PMID 14534844)
 KCI
 -
 6
 Yes#
 Eginton 2003 [17]

8
 No abstract
 -
 KCI (PMID 12625392)
 KCI
 -
 22
 Yes#
 Wanner 2003 [24]

9
 Joseph [79]
 The Cochrane Library
 KCI (No ID)
 KCI
 -
 24
 Yes#
 Joseph 2000 [19]

10
 Adams [26]
 NRR
 Unclear
 No reply
 Unclear
 Unclear
 No
 No

11
 Fryer [27]
 ClinicalTrials.gov
 Unclear
 No reply
 120
 Unclear
 No
 No

12
 McCarthy [28]
 NRR
 Unclear
 Author **
 160
 Unclear
 No
 No

13
 Walker [29]
 NRR
 Unclear
 No reply
 48
 Unclear
 No
 No
Subtotal
 13



328
 473

Discontinued









14
 No abstract
 -
 KCI (PMID 12142596)
 KCI
 -
 22
 Yes#
 Interim results: Ford 2002 [30]

15
 No abstract
 KCI
 KCI (VAC 2001–02)
 KCI
 214
 -
 No
 No

16
 Bayer [31]
 WUWHS 2004
 KCI (VAC 2002–09)
 KCI
 116
 -
 No
 No

17
 Greer [33]
 The Cochrane Library
 KCI (No ID)
 KCI
 †† 80
 -
 No
 No

18
 Orgill [34]
 WUWHS 2004
 KCI (VAC 2002–10)
 KCI
 116
 -
 No
 No

19
 Stannard [35]
 WUWHS 2004
 KCI (VAC 2001–06)
 KCI; author
 300
 -
 No
 No
Subtotal
 6



826
 22

Ongoing









20
 Armstrong [36]
 WUWHS 2004
 KCI (VAC 2001–08)
 KCI; author
 206
 -
 -
 No

21
 McCarthy [37]
 ClinicalTrials.gov
 Unclear
 No reply
 30
 -
 -
 No

22
 Molnar [38]
 WUWHS 2004
 KCI (VAC 2001–00)
 KCI
 50
 -
 -
 No

23
 Niezgoda [39]
 WUWHS 2004
 KCI (VAC 2001–01)
 KCI
 214
 -
 -
 No

24
 Stannard [40]
 WUWHS 2004
 KCI (VAC 2001–04)
 KCI; author
 258
 (44)
 Yes
 Interim results: Stannard 2006 [80]

25
 Stannard [41]
 WUWHS 2004
 KCI (VAC 2001–05)
 KCI; author
 348
 (44)
 Yes
 Interim results: Stannard 2006 [80]
Subtotal
 6



1106
 (88)

Unclear









26
 Foo [42]
 WUWHS 2004
 Unclear
 No reply
 Unclear
 -
 No
 No

27
 Gupta [43]
 WHS 2001
 Unclear
 No reply
 Unclear
 -
 No
 No

28
 Lantis [44]
 WUWHS 2004
 Unclear
 No reply
 Unclear
 -
 No
 No
Subtotal
 3



Unclear


Total (all trials)
 28



2260
 495

* Not classified by IQWiG as an RCT on NPWT (in contrast to other systematic reviews): McCallon 2000 [69]; Genecov 1998 [70]; Buttenschoen 2001 [81]; Jeschke 2004 [82].

† The PubMed ID number, when available, is used by KCI as the study ID for published RCTs.

‡ Number of patients planned in unpublished and ongoing studies as stated in abstracts and personal communications.

§ Number of patients analysed in published studies.

|| Full-text publication of interim or final results (any study status).

¶ Results considered in the IQWiG rapid report.

# Results considered in the IQWiG systematic review.

** The author replied to IQWiG's first request for information and stated that the trial was ongoing. However, according to information provided by the NRR (accessed on 04 Feb 2007), this trial has since been completed. A second query was not answered.

†† According to KCI, 16 patients were enrolled in this trial.

ID: Identification code; NRR: National Research Register; PMID: PubMed Identification Code; VLU: venous leg ulcer; WHS: Wound Healing Society; WUWHS: World Union of Wound Healing Societies.

Peinemann et al. BMC Medical Research Methodology 2008 8:4   doi:10.1186/1471-2288-8-4