Table 2

Parameter Values Used in the Simulated Data Sets

    Varied Parameter

    Assigned Values


Standard Deviation (percentage of control mean value)

10%, 40%, 70%

Number of Trials

5, 10, 30

Number of Experimental and Control Patients Per Trial Arm

10, 100

Effect Size (in standard deviation units)

0.2, 0.5, 0.8

Heterogeneity of Mean Values (in standard deviation units)

0, 0.5


Friedrich et al. BMC Medical Research Methodology 2008 8:32   doi:10.1186/1471-2288-8-32

Open Data