|
Reporting characteristics of the analysis of multiple genetic variants for 315 randomly selected HuGE articles (2001–2003) |
||
| Reporting characteristic |
Count |
Percent |
|
|
||
| Number of genes analyzed |
||
| 1 |
188 |
59.7 |
| 2 |
71 |
22.5 |
| >= 3 |
56 |
17.8 |
| Number of genetic variants analyzed |
||
| 1 |
114 |
36.2 |
| 2 |
85 |
27.0 |
| 3 |
56 |
17.8 |
| 4 |
21 |
6.6 |
| >= 5 |
39 |
12.4 |
| Reported on linkage disequilibrium (among those studying 2 or more polymorphisms) (n = 201) |
||
| No |
155 |
77.1 |
| Yes |
46 |
22.9 |
| Reported on an analysis using haplotypes (among those studying 2 or more polymorphisms) (n = 201) |
||
| No |
158 |
78.6 |
| Yes |
43 |
21.4 |
| Reported on a interlocus or gene-gene interaction (among those studying 2 or more polymorphisms) (n = 201) |
||
| No |
152 |
75.6 |
| Yes |
49 |
24.4 |
| If interlocus or gene-gene interactions were assessed, was risk quantified as an odds ratio or risk ratio (n = 49) |
||
| No |
22 |
44.9 |
| Yes |
27 |
55.1 |
| If interlocus or gene-gene interactions were assessed, was risk quantified as an absolute difference (n = 49) |
||
| No |
47 |
95.9 |
| Yes |
2 |
4.1 |
| If interlocus or gene-gene interactions were assessed, was risk quantified as an attributable fraction (n = 49) |
||
| No |
49 |
100.0 |
| Yes |
0 |
0.0 |
| If interlocus or gene-gene interactions were assessed, claim was made of a statistically significant interaction (n = 49) |
||
| No |
24 |
49.0 |
| Yes |
25 |
51.0 |
Yesupriya et al. BMC Medical Research Methodology 2008 8:31 doi:10.1186/1471-2288-8-31 |
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