Research article

The fallacy of enrolling only high-risk subjects in cancer prevention trials: Is there a "free lunch"?

Stuart G Baker¹^*, Barnett S Kramer² and Donald Corle¹

¹ Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, Bethesda, Maryland, USA

² Office of Disease Prevention, National Institutes of Health, Bethesda, Maryland, USA

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BMC Medical Research Methodology 2004, 4:24 doi:10.1186/1471-2288-4-24

Published: 4 October 2004

Additional File 1:

Appendix A, worked-out calculations of power.

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Additional File 2:

Appendix B, likelihood formulations

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