Table 2

Participant characteristic by baseline statin use
Baseline statin use
Non-weighted Weighted using stabilized IPTW1
Characteristics   No (N = 5150)   Yes (N = 885)   No (N = 5150)   Yes (N = 885)
Mean (SD) or n (%) Mean (SD) or n (%) P-value Mean (SD) or n (%) Mean (SD) or n (%) P-value
Age, Mean (SD), y 61.3 (10.3) 65.9 (8.8) <.001 62.0 (10.2) 62.9 (9.7) 0.141
Male 2441 (47.4%) 417 (47.1%) 0.879 2530 (47.7%) 401 (50.8%) 0.308
Race/ethnicity
White 1976 (38.4%) 385 (43.5%) 0.004 2069 (39.0%) 351 (44.5%) 0.156
Chinese 672 (13.1%) 99 (11.2%) 650 (12.3%) 74 (9.4%)
Black 1323 (25.7) 235 (26.6%) 1355 (25.6%) 186 (23.6%)
Hispanic 1179 (22.9%) 166 (18.8%) 1226 (23.1%) 178 (22.6%)
Body mass index, kg/m2 28.1 (5.5) 28.7 (5.0) <.001 28.2 (5.4) 28.5 (5.2) 0.235
Current smoker 690 (13.4%) 83 (9.4%) 0.001 659 (12.4%) 84 (10.6%) 0.394
Pack years smoking 11.0 (22.3) 12.9 (22.4) 0.021 11.1 (22.2) 10.9 (21.5) 0.880
Current alcohol use 2902 (56.4%) 507 (57.3%) 0.603 2997 (56.5%) 479 (60.7%) 0.128
Diabetes 534 (10.4%) 191 (21.6%) <.001 729 (13.8%) (111 (14.0%) 0.897
Family history of MI 1952 (37.9%) 427 (48.3%) <.001 2153 (59.4%) 334 (42.4%) 0.542
Hypertension 2082 (40.4%) 543 (61.4%) <.001 2301 (43.4%) 358 (45.3%) 0.492
Hypertension Meds 1645 (32.0%) 520 (58.8%) <.001 1941 (36.6%) 309 (39.2%) 0.323
Total cholesterol, mg/dL 196.7 (35.7) 224.1 (36.4) <.001 206.4 (50.9) 204.4 (41.2) 0.611
Systolic BP, mm Hg 125.5 (21.3) 129.7 (21.6) <.001 126.1 (21.1) 127.3 (22.3) 0.286
Diastolic BP, mm Hg 72.0 (10.4) 71.2 (9.6) 0.038 71.9 (10.3) 72.0 (9.9) 0.727
Health insurance 4644 (90.2%) 861 (97.3%) <.001 4789 (90.4%) 741 (93.9%) 0.109
Income
<$25 K 1586 (30.8%) 285 (32.2%) 0.165 1679 (31.7%) 229 (29.0%) 0.592
$25 K-$49 K 1492 (29.0%) 250 (28.3%) 1558 (29.4%) 237 (30.0%)
$50 K-$99 K 1375 (26.7%) 212 (24.0%) 1351 (25.5%) 198 (25.1%)
$100 K+ 697 (13.5%) 138 (15.6%) 712 (13.4%) 125 (15.9%)
Education
< High school 914 (17.8%) 143 (16.2%) 0.164 941 (17.8%) 124 (15.7%) 0.381
High school 2352 (45.7%) 420 (47.5%) 2475 (46.7%) 366 (46.4)
College 937 (18.2%) 142 (16.1%) 914 (17.3%) 124 (15.8%)
Graduate school 947 (18.4%) 180 (20.3%) 970 (18.3%) 174 (22.1%)
Married 3160 (61.4%) 546 (61.7%) 0.850 3246 (61.3%) 502 (63.6%) 0.406
Intentional exercise (met-min/wk) 1583 (2396) 1527 (2130) 0.480 1644 (2421) 1692 (2477) 0.705
Creatinine, mg/dL 0.94 (0.23) 1.01 (0.41) <.001 0.97 (0.31) 0.97 (0.30) 0.778
Fibrinogen, mg/dL 342.6 (72.8) 357.4 (74.6) <.001 351.3 (83.8) 356.4 (88.0) 0.530
hs-CRP, mg/L 3.7 (5.8) 3.2 (4.8) 0.004 3.6 (5.4) 4.2 (7.3) 0.396
CAC (Agatston) 122 (367) 240 (522) <.001 149 (400) 161 (444) 0.525
Common carotid (mm) 0.86 (0.19) 0.91 (0.19) <.001 0.87 (0.19) 0.88 (0.19) 0.195
Internal carotid (mm) 1.03 (0.57) 1.25 (0.67) <.001 1.08 (0.61) 1.13 (0.66) 0.139
Heart rate (bpm) 63.0 (9.5) 63.6 (9.8) 0.066 63.3 (9.8) 63.8 (10.4) 0.455

1 Comparisons for the first imputation.

Jorgensen et al.

Jorgensen et al. BMC Medical Research Methodology 2013 13:81   doi:10.1186/1471-2288-13-81

Open Data