Table 3

Results from four multinomial logistic regression analyses
Model 1: FPC1, FPC2 and FPC3 scores, gestational weeks 14–16*
2-h value, gestational weeks 30-32 n FPC1 scoresa FPC2 scores FPC3 scores
Mean (SD) OR (95% CI) p pb Mean (SD) OR (95% CI) p pb Mean (SD) OR (95% CI) p pb
≥8.84 19 12.6 (13.5) 1.08 (1.04,1.13) <0.001 0.40 5.7 (5.1) 1.36 (1.20,1.53) <0.001 0.01 −0.7 (3.0) 0.87 (0.68,1.10) 0.23 0.05
[7.8,8.84) 32 11.1 (13.1) 1.11 (1.07,1.14) <0.001 0.59 1.8 (4.7) 1.14 (1.04,1.25) 0.01 0.02 0.5 (1.6) 1.14 (0.95,1.37) 0.16 0.41
[6.90,7.8) 83 9.4 (12.8) 1.10 (1.07,1.12) <0.001 0.02 −0.1 (3.1) 1.01 (0.95,1.08) 0.69 0.60 0.2 (1.9) 1.05 (0.93,1.19) 0.47 0.57
[6.39,6.90) 94 4.9 (9.6) 1.06 (1.04,1.09) <0.001 −0.5 (3.8) 0.99 (0.93,1.06) 0.79 0.1 (1.8) 1.00 (0.89,1.13) 0.98
[3.89,6.39) 601 −1.8 (9.7) 1 Ref −0.2 (3.4) 1 Ref 0.1 (1.8) 1 Ref
[3.27,3.89) 70 −6.9 (8.7) 0.94 (0.91,0.98) <0.001 <0.01 0.0 (3.0) 0.98 (0.90,1.06) 0.62 0.07 −0.5 (1.7) 0.85 (0.74,0.98) 0.03 0.63
<3.27 23 −12.0 (9.8) 0.83 (0.78,0.90) <0.001 −0.9 (3.8) 0.85 (0.73,0.98) 0.02 −0.8 (2.4) 0.80 (0.62,1.01) 0.07
Model 2: Fasting value gestational weeks 14-16* Model 3: 2-h value gestational weeks 14-16* Model 5: Simple shape indexcgestational weeks 14-16*
Mean (SD) OR (95% CI) p pb Mean (SD) OR (95% CI) p pb Mean (SD) OR (95% CI) p pb
≥8.84 19 4.1 (0.5) 2.00 (0.57,6.86) 0.28 0.55 5.5 (1.4) 3.40 (2.24,5.18) <0.001 0.71 −0.80 (1.3) 0.53 (0.30,0.92) 0.03 0.36
[7.8,8.84) 32 4.1 (0.3) 3.17 (1.22,8.01) 0.02 0.54 5.3 (1.4) 3.11 (2.24,4.33) <0.001 0.07 −0.47 (0.8) 0.73 (0.46,1.17) 0.19 0.92
[6.90,7.8) 83 4.2 (0.4) 4.43 (2.26,7.71) <0.001 0.03 4.9 (1.1) 2.25 (1.79,2.84) <0.001 0.01 −0.47 (0.8) 0.71 (0.52,0.97) 0.03 0.84
[6.39,6.90) 94 4.1 (0.4) 1.87 (0.99,3.25) 0.04 4.4 (0.9) 1.58 (1.26,1.98) <0.001 −0.51 (0.7) 0.74 (0.55,1.00) 0.05
[3.89,6.39) 601 4.0 (0.4) 1 Ref 4.0 (0.9) 1 Ref −0.29 (0.7) 1 Ref
[3.27,3.89) 70 3.8 (0.3) 0.32 (0.15,0.65) <0.01 0.63 3.5 (0.8) 0.57 (0.42,0.78) <0.001 <0.01 −0.28 (0.7) 0.95 (0.66,1.37) 0.80 0.18
<3.27 23 3.8 (0.4) 0.23 (0.09,0.93) 0.01 2.9 (0.4) 0.24 (0.14,0.41) <0.001 −0.33 (1.1) 0.60 (0.34,1.07) 0.09

a The FPC1 scores in model 1 and the AUC in model 4 yielded nearly identical results and the AUC results are thus not shown.

bp values from pairwise comparison between adjacent groups.

cn=711. Calculated as 2-h value minus 90-min value, or 90-min minus 60-min value [12].

* Categories of 2-h values in the third trimester is the response variable and OGTT characteristics in gestational weeks 14–16 are explanatory variables. All models are adjusted for BMI in gestational weeks 14–16.

Frøslie et al.

Frøslie et al. BMC Medical Research Methodology 2013 13:6   doi:10.1186/1471-2288-13-6

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