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Learning from failure - rationale and design for a study about discontinuation of randomized trials (DISCO study)

Benjamin Kasenda†, Erik B von Elm†, John You, Anette Blümle, Yuki Tomonaga, Ramon Saccilotto, Alain Amstutz, Theresa Bengough, Jörg Meerpohl, Mihaela Stegert, Kari A O Tikkinen, Ignacio Neumann, Alonso Carrasco-Labra, Markus Faulhaber, Sohail Mulla, Dominik Mertz, Elie A Akl, Dirk Bassler, Jason W Busse, Ignacio Ferreira-González, Francois Lamontagne, Alain Nordmann, Rachel Rosenthal, Stefan Schandelmaier, Xin Sun, Per O Vandvik, Bradley C Johnston, Martin A Walter, Bernard Burnand, Matthias Schwenkglenks, Heiner C Bucher, Gordon H Guyatt and Matthias Briel*

  • * Corresponding author: Matthias Briel brielm@uhbs.ch

  • † Equal contributors

BMC Medical Research Methodology 2012, 12:131 doi:10.1186/1471-2288-12-131

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