Table 7

Number (%) of patients with functional status and quality of life measures at baseline

Score

Rheumatoid arthritis

Ankylosing spondylitis

Psoriatic arthritis

Psoriasis

Other a

Total


CGI-Severity

N [N missing]

190 [1]

43 [0]

42 [2]

35 [0]

19 [12]

329 [15]

Extremely ill

19 (10.0%)

0 (0.0%)

3 (7.1%)

5 (14.3%)

4 (21.1%)

31 (9.4%)

Severely ill

39 (20.5%)

15 (34.9%)

3 (7.1%)

8 (22.9%)

4 (21.1%)

69 (20.9%)

Markedly ill

66 (34.7%)

18 (41.9%)

17 (40.5%)

10 (28.6%)

3 (15.8%)

114 (34.7%)

Moderately ill

45 (23.7%)

7 (16.3%)

14 (33.3%)

5 (14.3%)

4 (21.1%)

75 (22.8%)

Mildly ill

13 (6.8%)

3 (7.0%)

3 (7.1%)

4 (11.4%)

2 (10.5%)

25 (7.6%)

Borderline

4 (2.1%)

0 (0.0%)

2 (4.8%)

3 (8.6%)

1 (5.3%)

10 (3.0%)

Normal

4 (2.1%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

1 (5.3%)

5 (1.5%)

Mean (SD) b

3.12 (1.28)

2.95 (0.90)

3.40 (1.13)

3.11 (1.49)

3.16 (1.77)

EQ VAS

N [N missing]

85 [106]

22 [21]

25 [19]

21 [14]

6 [25]

159 [185]

Mean (SD) b

49.5 (22.4)

42.2 (23.8)

45.6 (19.2)

50.7 (25.6)

50.5 (30.8)

48.1 (22.8)

Range

8.0-100.0

6.0-90.0

8.0-85.0

5.0-90.0

20.0-92.0

5.0-100.0

EQ-5D Index

N [N missing]

181 [10]

43 [0]

43 [1]

34 [1]

18 [13]

319 [25]

Mean (SD) c

0.40 (0.34)

0.37 (0.37)

0.42 (0.32)

0.52 (0.39)

0.51 (0.40)

0.42 (0.35)

Range

-0.24-1.00

-0.24-1.00

-0.24-0.80

-0.48-1.00

-0.35-1.00

-0.48-1.00


Disease specific

HAQ Score

DLQI Score

CHAQ Score

N [N missing]

190 [1]

-

-

35 [0]

9 [22]

Mean (SD)

1.74 (0.65)

-

-

15.0 (7.8)

1.35 (0.54)

Range

0.00-3.00

-

-

3.0-30.0

0.50-2.25

CHAQ Pain Score

N [N missing]

-

-

-

-

8 [23]

Mean (SD)

-

-

-

-

49.1 (30.1)

Range

-

-

-

-

7.0-90.0


a Includes patients with juvenile idiopathic arthritis (n = 9, 2.6%), patients responding other or not sure of condition (n = 10, 2.9%) and patients with condition missing (n = 12, 3.5%) to the question 'What condition do you have that is being treated with Enbrel?

b No significant differences in mean CGI-S or EQ-5D VAS scores between conditions using the Kruskal-Wallis test or ANOVA.

c No significant differences in mean CGI-S or EQ-5D VAS scores between conditions using the Kruskal-Statistically significant differences in EQ-5D Index scores between the conditions using the Kruskal-Wallis test (p = 0.043), but not with ANOVA, p = 0.259.

CHAQ Child Health Assessment Questionnaire (for patients with juvenile idiopathic arthritis), CGI Clinical Global Impression, DLQI Dermatology Life Quality Index (for patients with psoriasis), EQ EuroQoL, HAQ Health Assessment Questionnaire (for patients with rheumatoid arthritis), VAS Visual analogue scale

Wade et al. BMC Medical Research Methodology 2011 11:91   doi:10.1186/1471-2288-11-91

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