Table 5

Use of methotrexate at baseline

Rheumatoid arthritis

Ankylosing spondylitis

Psoriatic arthritis

Psoriasis a

Other b

Total


N [N missing]

190 [1]

43 [0]

44 [0]

35 [0]

19 [12]

331 [13]

Taking methotrexate

No, n (%)

71 (37.4%)

38 (88.4%)

27 (61.4%)

31 (88.6%)

11 (57.9%)

178 (53.8%)

Unsure, n (%)

1 (0.5%)

2 (4.7%)

1 (2.3%)

0 (0.0%)

0 (0.0%)

4 (1.2%)

Yes, n (%)

118 (62.1%)

3 (7.0%)

16 (36.4%)

4 (11.4%)

8 (42.1%)

149 (45.0%)

Route of administration

Tablets, n (%)

97 (82.2%)

3 (100.0%)

11 (68.8%)

3 (75.0%)

6 (75.0%)

120 (80.5%)

Injection, n (%)

21 (17.8%)

0 (0.0%)

5 (31.2%)

1 (25.0%)

2 (25.0%)

29 (19.5%)

Weekly dose

N [N missing]

116 [2]

3 [0]

16 [0]

4 [0]

7 [1]

146 [3]

Mean (SD)

16.6 (6.8)

17.5 (2.5)

15.6 (7.3)

16.2 (9.7)

13.6 (8.9)

16.4 (6.9)

Range

2.5-30.0

15.0-20.0

2.5-25.0

2.5-25.0

2.5-25.0

2.5-30.0

Feedback received

Yes, n (% of not taking)

40 (56.3%)

21 (55.3%)

19 (70.4%)

16 (51.6%)

5 (45.5%)

101 (56.7%)

Ever prescribed c

No, n (%)

1 (2.5%)

18 (85.7%)

0 (0.0%)

5 (31.2%)

1 (20.0%)

25 (24.8%)

Unsure, n (%)

1 (2.5%)

1 (4.8%)

0 (0.0%)

1 (6.2%)

0 (0.0%)

3 (3.0%)

Yes, n (%)

38 (95.0%)

2 (9.5%)

19 (100.0%)

10 (62.5%)

4 (80.0%)

73 (72.3%)

Reason stopped d

Lack of effect, n (%)

6 (15.8%)

1 (50.0%)

1 (5.3%)

4 (40.0%)

0 (0.0%)

12 (16.4%)

Side effects, n (%)

27 (71.1%)

1 (50.0%)

16 (84.2%)

5 (50.0%)

3 (75.0%)

52 (71.2%)

Doctor stopped, n (%)

5 (13.2%)

0 (0.0%)

2 (10.5%)

1 (10.0%)

1 (25.0%)

9 (12.3%)

Unsure, n (%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

0 (0.0%)


a Twenty-five patients (71.4%) with psoriasis were also using creams for the condition at baseline, but none of the patients had undergone phototherapy treatment.

b Includes patients with juvenile idiopathic arthritis (n = 9, 2.6%), patients responding other or not sure of condition (n = 10, 2.9%) and patients with condition missing (n = 12, 3.5%) to the question 'What condition do you have that is being treated with Enbrel?

c Data for feedback responders (Respondents answering "no" to the question " Are you taking methotrexate" at baseline and providing feedback on any previous use)

d Data for feedback responders ever prescribed methotrexate (Feedback respondents answering "yes" to the question " Have you ever been prescribed methotrexate")

Wade et al. BMC Medical Research Methodology 2011 11:91   doi:10.1186/1471-2288-11-91

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