Table 1

Summary table of scope of reviews in a systematic review of reviews1



Aim (participants)

Search strategy

No. of studies included

Total no. of participants

Timing of preventative strategy

King & Flenady 2002

To assess the effects of prophylactic antibiotics on preterm labour (women symptomatic for preterm labour)

Cochrane Pregnancy & Childbirth Group (May 2002)

Search terms provided.

No language restrictions


7428 (6295 enrolled in one trial)

Mean gestational age at entry to all trials 30-32 weeks (but varied across studies)

Simcox et al 2007

To determine if antibiotics reduce the risk of preterm birth (asymptomatic women at risk, e.g. previous preterm birth or positive fibronectin status)

Cochrane Pregnancy & Childbirth Group (2005)

Search terms provided.

English language publications.



12-28 weeks across studies

1Reprinted from the European Journal of Obstetrics & Gynecology and Reproductive Biology, Volume 142, Smith V, Devane D, Begley CM, Clarke M, Higgins S. A systematic review and quality assessment of systematic reviews of randomised trials of interventions for preventing and treating preterm birth. 3-11, Copyright (2009), with permission from Elsevier.

Smith et al. BMC Medical Research Methodology 2011 11:15   doi:10.1186/1471-2288-11-15

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