Table 5

Observed disease status and Test 2 results in a test if negative trial design

Test 2

Observed Disease Status

Probability


+

+

pD [FN(1) - FN(1, 2)]/Q

+

-

(1 - pD)FP(2)/Q

-

+

pDpEFN(1,2)/Q

-

-

[(1 - pD)TN(2) + pD(1 - pE)FN(1, 2)/Q


Ringham et al. BMC Medical Research Methodology 2010 10:3   doi:10.1186/1471-2288-10-3

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