Flowchart for single test design. Flowchart depicts a single test screening trial from an omniscient point of view. Dashed lines indicate a pathway that is unavailable to that class of participants (true case or true non-case) due to the assumptions of our model. The gray box indicates cases that are misclassified as noncases by the study investigator.
Ringham et al. BMC Medical Research Methodology 2010 10:3 doi:10.1186/1471-2288-10-3