Table 2 |
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|
Summary results for efficacy of paracetamol/codeine combinations and active comparators in randomised, double-blind, active- and placebo-controlled trials in acute pain |
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|
Drug/dose |
Number of |
Patients with at |
Percentage |
|
trials |
least 50% pain |
(95%CI) |
|
|
relief/total |
|||
|
|
|||
|
Paracetamol 300 mg + codeine 30 mg |
3 |
67/272 |
25 (20 to 30) |
|
Codeine 60 mg |
3 |
24/72 |
33 (22 to 44) |
|
Ibuprofen 400 mg |
2 |
28/72 |
39 (28 to 50) |
|
Paracetanol 600/650 mg |
10 |
135/311 |
43 (38 to 49) |
|
Paracetamol 1000 mg |
4 |
64/151 |
42 (35 to 50) |
|
Paracetamol 600 mg + codeine 60 mg |
13 |
191/398 |
48 (43 to 53) |
|
Diflusinal 500 mg |
3 |
54/90 |
60 (50 to 70) |
|
Ketorolac 10 mg |
3 |
75/117 |
64 (55 to 73) |
|
Diflusinal 1000 mg |
3 |
61/92 |
66 (57 to 76) |
|
Paracetamol 1000 mg + codeine 60 mg |
6 |
150/229 |
66 (59 to 72) |
|
Flurbiprofen 50 mg |
3 |
69/99 |
70 (61 to 79) |
|
Flurbiprofen 100 mg |
3 |
70/92 |
76 (67 to 85) |
|
|
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|
Smith et al. BMC Medical Research Methodology 2001 1:1 doi:10.1186/1471-2288-1-1 |
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