Table 4

Sensitivity, specificity, positive and negative predictive values for the diagnosis of ACS with myocyte necrosis or clinical myocardial infarction at presentation

Sensitivity (95% CI)

Specificity (95% CI)

Positive predictive value (95% CI)

Negative predictive value (95% CI)


Serial ECG & ST monitoring N = 690

23.3% (14.4 to 35.4)

95.7% (93.8 to 97.0)

34.1% (21.6 to 49.5)

92.9% (90.7 to 94.6)

Initial CK-MB(mass) N = 687

43.3% (31.6 to 55.9)

97.9% (96.5 to 98.8)

66.7% (51.0 to 79.4)

94.8% (92.8 to 96.2)

Delayed CK-MB(mass) N = 601

63.5% (49.9 to 75.2)

98.0% (96.4 to 98.9)

75.0% (60.6 to 85.4)

96.6% (94.7 to 97.8)

Delta CK-MB(mass) N = 601

55.8% (42.3 to 68.4)

99.6% (98.7 to 99.9)

93.5% (79.3 to 98.2)

96.0% (94.0 to 97.3)

Any positive CK-MB(mass) N = 601

71.7% (59.2 to 81.5)

97.4% (95.9 to 98.4)

72.9% (60.4 to 82.6)

97.3% (95.7 to 98.3)

Troponin T > = 0.1 ng/ml N = 686

55.0% (42.5 to 66.9)

100% (99.4 to 100)

100% (89.6 to 100)

96.0% (94.2 to 97.2)

Troponin T > = 0.03 ng/ml N = 686

89.7% (79.2 to 95.2)

99.7% (98.8 to 99.9)

96.3% (87.5 to 99.0)

99.6% (97.9 to 99.9)


Goodacre et al. BMC Emergency Medicine 2005 5:6   doi:10.1186/1471-227X-5-6

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