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This article is part of the supplement: Abstracts from the 2012 PLA Emergency Medicine Annual Congress

Open Access Meeting abstract

Clinical usefulness of T-SPOT.TB in the diagnosis tuberculosis in emergency patients

HU Xiao-min, LIU Jian, LEI Long and YIN Wen*

Author Affiliations

Department of Emergency Xijing Hospital, the Fourth Military Medical University, Changle Xilu Road No.127, Xi'an 710032, China

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BMC Emergency Medicine 2012, 12(Suppl 1):A7  doi:10.1186/1471-227X-12-S1-A7

The electronic version of this article is the complete one and can be found online at:

Published:18 December 2012

© 2012 Xiao-min et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


To evaluate the diagnostic value of an interferon-gamma release assay T-SPOT.TB in tuberculosis of emergency patients.


The emergency patients with suspected tuberculosis received T-SPOT.TB assay in the peripheral blood mononuclear cells(PBMCs).


T-SPOT.TB assay, PPD, anti-TB antibody test, M tuberculosis polymerase chain reaction, acid-fast bacilli stain and cultures for M tuberculosis were positive in 96.8%(31/32), 43.7%(14/32), 21.8%(7/32), 15.6%(5/32), 13.0%(3/23) and 4.3%(1/23), respectively, of patients with active tuberculosis. The sensitivity and specificity of the T-SPOT.TB were 96.8% and 98.3%.


T-SPOT.TB assay is a rapid and high-sensitive tests for diagnosing tuberculosis in emergency patients.