Table 2

Search Strategy

Database

Pub Med

Ovid Medline

EMBASE


    Dates searched

1/1/1990 - 12/31/2009

1/1/1990 - 12/31/2009

1990 - 2009


    Search terms employed (all connected by logical "OR" function)

    MeSH headings:

    MeSH headings:

Crotalid venoms/PO [poisoning]

Crotalid venoms/PO [poisoning]

Crotalid venoms AND [intoxication OR toxicity]

Crotalid venoms/TO [toxicity]

Crotalid venoms/TO [toxicity]

Snake venoms AND [intoxication OR toxicity]

Snake venoms/PO

Snake venoms/PO

Snake bites AND [drug therapy OR therapy]

Snake venoms/TO

Snake venoms/TO

Snake bites/DT [drug therapy]

Snake bites/DT [drug therapy]

Viperidae

Snake bites/TH [therapy]

Snake bites/TH [therapy]

Agkistrodon

Viperidae

Viperidae

Crotalus

Agkistrodon

Agkistrodon

FabAV

Crotalus

Crotalus

Crotaline immune Fab

    Keywords

    Keywords

CroFab

CroFab

Crotaline immune Fab

Crotaline immune Fab


    Citations retrieved

    1230

    1097

1711


Searches were conducted on January 6, 2010 and were limited to English language and humans. After removal of 1,748 duplicate citations, 339 additional citations were excluded based on the keywords rat(s), mouse, mice, rabbit(s), cellular, in vivo, or in vitro. Hand-search of the titles and abstracts of the remaining 1,951 citations yielded 91 citations that appeared to contain original data about crotaline snake envenomation patients who were either treated with Fab antivenom or managed without antivenom. Full-text copies of these 91 articles and abstracts were obtained and made available to the project team in a computer data file. Of these, 42 articles and abstracts were identified as containing data relevant to the key questions identified in preliminary panel discussions. These 42 references were reproduced and made available during the in-person panel meeting.

Lavonas et al. BMC Emergency Medicine 2011 11:2   doi:10.1186/1471-227X-11-2

Open Data