Table 2

Risk of paroxysmal atrial fibrillation associated with age, sex, and other factors

Paroxysmal AF cases

Controls

n = 525

(%)

n = 5000

(%)

OR*

(95% CI)

Age

40–49

31

(5.9)

1565

(31.3)

1

50–59

62

(11.8)

1343

(26.9)

2.1

(1.3–3.2)

60–69

131

(25.0)

997

(19.9)

5.0

(3.3–7.5)

70–79

188

(35.8)

769

(15.4)

8.3

(5.5–12.5)

80–89

113

(21.5)

326

(6.5)

10.9

(7–17.1)

Sex

Female

268

(51.0)

2647

(52.9)

1

Male

257

(49.0)

2353

(47.1)

1.3

(1.0–1.6)

Smoking†

Non-smoker

313

(59.6)

2736

(54.7)

1

Smoker

94

(17.9)

1226

(24.5)

0.8

(0.6–1.0)

Ex-smoker

42

(8.0)

280

(5.6)

1.0

(0.7–1.5)

Body mass index (BMI) †

<20

25

(4.8)

201

(4.0)

1.4

(0.9–2.4)

20–24

135

(25.7)

1466

(29.3)

1

25–29

162

(30.9)

1420

(28.4)

1.1

(0.8–1.4)

30+

62

(11.8)

601

(12.0)

1.1

(0.8–1.5)

Alcohol consumption (units per week) †#

None

185

(35.2)

1597

(31.9)

1

1–7 units

114

(21.7)

1112

(22.2)

1.2

(0.9–1.6)

8–21 units

69

(13.1)

718

(14.4)

1.4

(1.0–1.9)

>21 units

31

(5.9)

292

(5.8)

1.7

(1.1–2.6)

Comorbidity

IHD

156

(29.7)

415

(8.3)

2.1

(1.6–2.6)

Valvular disease

30

(5.7)

41

(0.8)

4.2

(2.4–7.3)

Heart failure

81

(15.4)

117

(2.3)

2.5

(1.8–3.5)

Hypertension

197

(37.5)

859

(17.2)

1.4

(1.2–1.8)

Cerebrovascular disease

68

(13.0)

195

(3.9)

1.5

(1.1–2.1)

Diabetes

36

(6.9)

194

(3.9)

0.9

(0.6–1.4)

Hyperthyroidism

19

(3.6)

44

(0.9)

3.6

(2.0–6.5)

*OR: Odds ratio adjusted by age, sex and all the variables in the table, using unconditional logistic regression.

†Missing data in smoking (15.1%), BMI (26.3%) and alcohol use (25.5%).

# 1 unit = 10 mL of pure ethanol.

Ruigómez et al. BMC Cardiovascular Disorders 2005 5:20   doi:10.1186/1471-2261-5-20