|
Raw data for aortic regurgitation (mild or greater). When duration of exposure was reported as a range, the midpoint of the range is given here. "Time off" refers to the time between the last dose of anorexic and the echocardiogram. |
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| Author, year |
Mean Age |
Fen dose (mg/day) |
Dexfen dose (mg/day) |
Duration (months) |
Time off (months) |
Controls (N) |
Affected in Controls |
Exposed (N) |
Affected in Exposed |
|
|
|||||||||
| Khan, 1998 |
46.0 |
90 |
0 |
26.5 |
3.9 |
233 |
3 |
163 |
41 |
| 43.0 |
0 |
30 |
4.9 |
3.9 |
39 |
4 |
|||
| 44.7 |
0 |
30 |
9.0 |
3.9 |
31 |
6 |
|||
| Weissman, 1998 |
45.1 |
0 |
30 |
2.4 |
1.3 |
330 |
12 |
671 |
36 |
| Shively, 1999 |
50.0 |
0 |
30 |
6.9 |
8.5 |
189 |
4 |
223 |
14 |
| Hensrud, 1999 |
42.0 |
40 |
0 |
9.6 |
1.5 |
11 |
1 |
19 |
5 |
| Ryan, 1999 |
49.1 |
60 |
30 |
16.7 |
12.2 |
0 |
0 |
79 |
13 |
| Gardin, 2000 |
46.9 |
46 |
0 |
2.0 |
6.8 |
536 |
22 |
48 |
2 |
| 46.9 |
46 |
0 |
4.5 |
6.8 |
115 |
15 |
|||
| 46.9 |
46 |
0 |
9.0 |
6.8 |
117 |
13 |
|||
| 46.9 |
46 |
0 |
15.0 |
6.8 |
86 |
14 |
|||
| 46.9 |
46 |
0 |
22.0 |
6.8 |
85 |
18 |
|||
| 48.4 |
0 |
29 |
2.0 |
5.3 |
92 |
0 |
|||
| 48.4 |
0 |
29 |
4.5 |
5.3 |
183 |
15 |
|||
| 48.4 |
0 |
29 |
9.0 |
5.3 |
166 |
23 |
|||
| 48.4 |
0 |
29 |
15.0 |
5.3 |
29 |
4 |
|||
| Jollis, 2000 |
46.1 |
60 |
0 |
2.0 |
15 |
669 |
24 |
25 |
1 |
| 46.1 |
60 |
0 |
4.5 |
15 |
313 |
14 |
|||
| 46.1 |
60 |
0 |
9.0 |
15 |
415 |
29 |
|||
| 46.1 |
60 |
0 |
18.0 |
15 |
315 |
43 |
|||
| 46.1 |
60 |
0 |
30.0 |
15 |
86 |
15 |
|||
| Davidoff, 2001 |
48.8 |
60 |
0 |
2.5 |
53 |
254 |
11 |
276 |
17 |
Hopkins and Polukoff BMC Cardiovascular Disorders 2003 3:5 doi:10.1186/1471-2261-3-5 |
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