Table 2 |
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|
Effect of treatment on body temperature (in °C) and outcome. Effects on area under the curve measurements were adjusted for body temperature at start of treatment. |
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|
Acetaminophen N = 25 |
Ibuprofen N = 24 |
Placebo N = 25 |
|
|
|
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|
Temperature at 24 hrs (mean, SD) |
37.2 (0.5) |
37.2 (0.4) |
37.2 (0.5) |
|
Difference with placebo (95% CI) |
0 (-.3 to 0.3) |
0 (-.3 to 0.3) |
- |
|
Change in temperature at 24 hrs, (mean, SD) |
-0.1 (0.6) |
0.1 (0.6) |
0.2 (0.5) |
|
Difference with placebo (95% CI) |
0.3 (0 to 0.6) |
0.1 (-.3 to 0.4) |
- |
|
Change in temperature after 5 days in(SD) |
0.3 (1.2) |
0.6 (1.6) |
0.1 (0.6) |
|
Difference with placebo (95% CI) |
-.2 (-1.0 to 0.7) |
-.5 (-1.2 to 0.2) |
- |
|
Area under the curve (first 24 hours) in hrs × °C (SD) |
888 (12) |
883 (16) |
893 (14) |
|
Difference with placebo (95% CI) |
7 (0 to 12) |
7 (2 to 12)) |
- |
|
Area under the curve (5 days) in hrs × °C (SD) |
4443 (63) |
4367 (128) |
4438 (64) |
|
Difference with placebo (95% CI) |
9 (-52 to 34) |
23 (-15 to 62) |
- |
|
N of patients with Modified Rankin score >2, (%) |
13 (52%) |
9 (38%) |
12 (48%) |
|
N of patients with Barthel index <20 (%) |
14 (56%) |
10 (42%) |
14 (56%) |
|
|
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Dippel et al. BMC Cardiovascular Disorders 2003 3:2 doi:10.1186/1471-2261-3-2 |
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