Table 3

Results of meta-analysis in each group and mean CAP volume in each group at baseline and follow up
    Group Included arms (case) CAP Volume at Baseline (mm3) CAP Volume at Follow up (mm3) Pooled SMD (95% CI, p ) Heterogeneity test Sensitivity analyses Egger’s test
χ2test ( p ) I2 Lower SMD (95% CI) Upper SMD (95% CI)
≤70 mg 7 (1250) 177.1±41.9 125.9±38.6 -0.156 (-0.235~ -0.078, 0.000) 0.57 (0.997) 0 -0.146 (-0.238~ -0.054) -0.167 (-0.270~ -0.064) 0.835
Without 2006 ASTEROID Ros Without 2011 SATURN Ros
>70≤100HP mg 11 (1352) 129.7±72.3 123.8±69.8 -0.123 (-0.199~ -0.048, 0.001) 6.83 (0.741) 0 -0.103 (-0.182~ -0.024) -0.151 (-0.235~ -0.067) 0.501
Without 2009 JAPAN-ACS Ato Without 2004 REVERSAL Ato
>70≤100MP mg 5 (1548) 195.8±2.3 191.8±4.7 -0.045 (-0.115~ -0.026, 0.215) 1.59 (0.811) 0 -0.016 (-0.103~ -0.066) -0.061 (-0.140~ -0.019) 0.500
Without 2007 ILLUSTRATE Ato+Tor Without 2008 STRADIVARIUS Con
>70≤100LP mg 6 (1061) 201.2±15.1 197.3±15.0 -0.045 (-0.130~0.040, 0.301) 1.14 (0.950) 0 -0.024 (-0.136~ 0.087) -0.059 (-0.148~ 0.031) 0.241
Without 2007 ILLUSTRATE Ato Without 2004 A-PLUS Ava 50
>100 mg 10 (669) 175.9±86.4 178.7±89.1 0.017 (-0.090~0.124, 0.757) 2.37 (0.984) 0 -0.000 (-0.135~ 0.136) 0.039 (-0.073~ 0.151) 0.692
Without 2004 REVERSAL Pro Without 2005 Tani S Pra
<0% 8 (1276) 201.2±13.8 198.3±13.8 -0.034 (-0.111~ 0.044, 0.396) 1.55 (0.981) 0 -0.012 (-0.109~ 0.084) -0.044 (-0.125~ 0.037) 0.087
Without 2007 ILLUSTRATE Ato Without 2004 A-PLUS Ava 50
>0≤30% 13 (2014) 188.6±51.7 186.3±52.7 -0.032 (-0.093~ 0.030, 0.315) 4.59 (0.970) 0 -0.010 (-0.080~ 0.061) -0.042 (-0.108~ 0.024) 0.537
Without 2007 ILLUSTRATE Ato+Tor Without 2004 REVERSAL Pra
>30≤40% 10 (594) 102.9±96.9 94.3±90.4 -0.199 (-0.314~ -0.085, 0.001) 3.10 (0.960) 0 -0.166 (-0.295~ -0.038) -0.214 (-0.342~ -0.085) 0.024
Without 2009 JAPAN-ACS Ato Without 2009 COSMOS Ros
>40≤50% 8 (1677) 157.8±37.8 150.7±36.3 -0.108 (-0.176~ -0.040, 0.002) 2.50 (0.927) 0 -0.093 (-0.174~ -0.011) -0.126 (-0.200~ -0.053) 0.605
Without 2011 SATURN Ros Without 2004 REVERSAL Ato
>50% 1 (349) 212.2±81.3 197.5±79.1 -0.183 (-0.332~ -0.035, 0.016)

Gao et al.

Gao et al. BMC Cardiovascular Disorders 2014 14:60   doi:10.1186/1471-2261-14-60

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