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Open Access Highly Accessed Research article

Association between smoking status and the parameters of vascular structure and function in adults: results from the EVIDENT study

Jose I Recio-Rodriguez1*, Manuel A Gomez-Marcos1, Maria C Patino Alonso2, Carlos Martin-Cantera3, Elisa Ibañez-Jalon4, Amor Melguizo-Bejar5, Luis Garcia-Ortiz1 and on behalf of the EVIDENT Group

Author Affiliations

1 La Alamedilla Health Centre, Castilla y León Health Service–SACYL, redIAPP, IBSAL, Salamanca, Spain

2 Statistics Department, University of Salamanca, Salamanca, Spain

3 Passeig de Sant Joan Health Centre, Catalan Health Service, Barcelona, Spain

4 Casa de Barco Health Centre, Castilla y León Health Service–SACYL, Valladolid, Spain

5 Torre Ramona Health Centre, Aragón Health Service, Zaragoza, Spain

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BMC Cardiovascular Disorders 2013, 13:109  doi:10.1186/1471-2261-13-109

Published: 1 December 2013

Abstract

Background

The present study analyses the relation between smoking status and the parameters used to assess vascular structure and function.

Methods

This cross-sectional, multi-centre study involved a random sample of 1553 participants from the EVIDENT study. Measurements: The smoking status, peripheral augmentation index and ankle-brachial index were measured in all participants. In a small subset of the main population (265 participants), the carotid intima-media thickness and pulse wave velocity were also measured.

Results

After controlling for the effect of age, sex and other risk factors, present smokers have higher values of carotid intima-media thickness (p = 0.011). Along the same lines, current smokers have higher values of pulse wave velocity and lower mean values of ankle-brachial index but without statistical significance in both cases.

Conclusions

Among the parameters of vascular structure and function analysed, only the IMT shows association with the smoking status, after adjusting for confounders.

Keywords:
Smoking; Carotid intima-media thickness; Vascular stiffness