Dysfunctions of the coronary endothelium as well as injury to cardiac muscle cells are the consequences of Dox effect among many factors, MCP-1and ICAM-1 expression are released into the myocardium and circulation. Data are expressed as mean ± SEM, (A) MCP-1 #*P < 0.05; vs. Dox only (n = 8 per group). (B) While the representative western blots showing increased ICAM-1 protein expression in Dox only group #*P < 0.05; vs. Dox only (n = 8 per group).
Hadi et al. BMC Cardiovascular Disorders 2012 12:63 doi:10.1186/1471-2261-12-63