Neointima on grafts harvested 24 weeks after the surgery(× 400). White arrows indicate endothelial cells, black arrows vascular grafts, and red arrows smooth muscle cells. (A) A PU graft stained for von Willebrand factor (vWF) showing continuous endothelial layer. (B) A PTFE graft stained for vWF showing continuous endothelial layer. (C) A PU graft stained for α-SM-actin showing an orderly arrangement of smooth muscle cells without further increase of neointimal thickness. (D) A PTFE graft stained for α-SM-actin showing disordered arrangement of smooth muscle cells and increased neointima thickness.
Hu et al. BMC Cardiovascular Disorders 2012 12:115 doi:10.1186/1471-2261-12-115