Table 4 |
|||||||
| Characteristics of the study sample of patients stratified according to IMT | |||||||
| Normal | Thickening | Plaque | P Values | ||||
| ANOVA or χ2 | Normal vs Thickening | Normal vs Plaque | Thickening vs Plaque | ||||
| Age (years) | 47.3 ± 13.3 | 57.0 ± 9.6 | 65.9 ± 9.8 | <0.001 | 0.004 | <0.001 | 0.001 |
| Sex (male/female) | 16/10 | 10/12 | 101/51 | 0.157 | |||
| Family history of hypertension (yes/no) | 16/10 | 18/4 | 79/73 | 0.026 | |||
| Family history of stroke (yes/no) | 4/22 | 6/16 | 29/123 | 0.564 | |||
| Smokers (yes/ex/no) | 4/3/19 | 6/2/14 | 25/37/90 | 0.242 | |||
| Diabetes (yes/no) | 2/24 | 1/21 | 17/135 | 0.572 | |||
| Diastolic BP (mmHg) | 76.5 ± 10.8 | 73.4 ± 18.6 | 75.8 ± 11.1 | 0.643 | 1 | 1 | 1 |
| Systolic BP (mmHg) | 131.5 ± 19.2 | 124.1 ± 33.2 | 134.8 ± 21.1 | 0.106 | 0.768 | 1 | 0.113 |
| Pulse pressure (mmHg) | 55.0 ± 14.9 | 50.6 ± 19.9 | 59.0 ± 17.8 | 0.086 | 1 | 0.856 | 0.117 |
| Fasting blood glucose (mmHg) | 98.0 ± 20.7 | 95.7 ± 22.0 | 104.5 ± 24.7 | 0.154 | 1 | 0.601 | 0.321 |
| Total Cholesterol (mg/dl) | 182.0 ± 38.0 | 192.0 ± 39.1 | 185.6 ± 41.4 | 0.687 | 1 | 1 | 1 |
| BMI (kg/m2) | 28.8 ± 5.4 | 27.3 ± 3.7 | 27.6 ± 4.6 | 0.395 | 0.747 | 0.596 | 1 |
| Beta-blockers (yes/no) | 15/11 | 6/16 | 46/106 | 0.019 | |||
| Alphabeta-blockers (yes/no) | 1/25 | 3/19 | 17/135 | 0.465 | |||
| Alpha-blockers (yes/no) | 1/25 | 2/20 | 13/139 | 0.702 | |||
| Diuretics (yes/no) | 9/17 | 8/14 | 70/82 | 0.429 | |||
| ACE inhibitor (yes/no) | 10/16 | 8/14 | 57/95 | 0.989 | |||
| Dihydropyridine (yes/no) | 7/19 | 4/18 | 41/111 | 0.675 | |||
| eGFR (mL/min/1.73 m2) | 84.1 ± 17.5 | 81.2 ± 17.8 | 75.2 ± 19.1 | 0.045 | 1 | 0.077 | 0.479 |
| Renal involvement | 9/15/2 | 6/13/3 | 33/91/28 | 0.502 | |||
| IMT (mm) | 0.89 ± 0.11 | 1.19 ± 0.08 | 2.62 ± 1.61 | <0.001 | 1 | <0.001 | <0.001 |
| LVMi g/m2 | 109.6 ± 19.0 | 126.7 ± 33.2 | 134.6 ± 30.9 | <0.001 | 0.149 | <0.001 | 0.744 |
| Left Ventricular hypertrophy (no/yes) | 20/6 | 11/11 | 49/103 | <0.001 | |||
Data are expressed as mean and standard deviation for continuous variables (i.e. age) and as number of patients per each group for categorical variable (i.e. gender).
The p-value refers to ANOVA and post-hoc comparison with Bonferroni corrections for continuous variables and to χ2 for categorical variables.
Melillo et al. BMC Cardiovascular Disorders 2012 12:105 doi:10.1186/1471-2261-12-105
