Table 1 |
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|
Clinical characteristics |
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|
Normal DF (n = 30) |
mild LVDD (n = 51) |
HFnEF (n = 49) |
p-value |
All (n = 130) |
|
|
|
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|
Clinical variables |
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|
Age (years) |
60 (50-66) |
65 (57-69) |
72 (67-76) |
<0.001* |
67 (59-73) |
|
Female gender |
15 (50) |
21 (41) |
28 (57) |
0.278 |
64 (49) |
|
BMI (kg/m2) |
26 (24-32) |
27 (25-31) |
28 (25-31) |
0.236 |
27 (25-32) |
|
Systolic BP (mmHg) |
123 (110-130) |
130 (126-142) |
138 (130-140) |
<0.001* |
130(122-140) |
|
Diastolic BP (mmHg) |
76 (70-80) |
80 (76-86) |
80 (70-84) |
0.023* |
80(70-83) |
|
CAD |
16 (53) |
31 (61) |
34 (69) |
0.346 |
81 (62) |
|
Previous MI |
7 (23) |
7 (14) |
14 (29) |
0.189 |
28 (22) |
|
Previous stroke |
0 |
2 (4) |
2 (4) |
0.339 |
4 [39] |
|
Previous PTCA |
14 (46) |
25 (496) |
25 (51) |
0.905 |
64 (49) |
|
Cardiovascular risk factors |
|||||
|
Treated hypertension |
23 (77) |
46 (90) |
47 (96) |
0.010* |
116 (89) |
|
Smoking |
7 (23) |
8 (16) |
6(12) |
0.041* |
21 (16) |
|
Family history CAD |
15 (50) |
29 (57) |
20 (42) |
0.669* |
64 (50) |
|
Hyperlipidaemia |
14 (46) |
38 (74) |
33 (67) |
0.037* |
85 (65) |
|
Glucose metabolism status |
|||||
|
NGT |
13 (43) |
13 (25) |
12 (24) |
0.013* |
38 (29) |
|
IGT |
11 (37) |
13 (25) |
10 (20) |
34 (26) |
|
|
New detected T2DM |
3 (10) |
8 (16) |
12 (24) |
23(18) |
|
|
Known T2DM |
3 (10) |
17 (33) |
15 (31) |
35 (29) |
|
|
Medications |
|||||
|
ACE inhibitor |
17 (56) |
29 (57) |
34 (69) |
0.359 |
80 (61) |
|
AT1 blocker |
2 (7) |
8 (16) |
11 (22) |
0.179 |
21 (16) |
|
Diuretics |
5 (17%) |
12 (24) |
24 (49) |
0.003* |
41 (32) |
|
Ca2+ blocker |
4 (13) |
6 (12) |
17 (34) |
0.011* |
27 (21) |
|
ß-Blocker |
21 (70%) |
32 (63) |
42 (86) |
0.032* |
95 (73) |
|
Insulin therapy |
0 |
8 (20) |
6 (15) |
0.128 |
14 (11) |
|
OAD |
1 (6) |
13 (34) |
5 (12) |
0.012* |
19 (15) |
|
|
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|
Values are median (interquartile range) or n (%), * statistically significant (p < 0.05). BMI = Body mass index, BP = blood pressure, CAD = Coronary Artery Disease, CABG = coronary bypass graft, DF = diastolic function, HFnEF = heart failure with normal ejection fraction, IGT = impaired glucose tolerance, LVDD = left ventricular diastolic dysfunction, NGT = normal glucose tolerance, OAD = oral anti-diabetic therapy, PTCA = percutaneous coronary angioplasty, T2DM = type 2 diabetes mellitus |
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|
Dinh et al. BMC Cardiovascular Disorders 2011 11:41 doi:10.1186/1471-2261-11-41 |
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