Table 2 

Predictors of 10year coronary heart disease without and with adjustment for time dependent traditional risk factors 

Model 1 
Model 2 
Model 3 
Model 4 



HR (95% CI) 
HR (95% CI) 
HR (95% CI) 
HR (95% CI) 







Framingham Risk Score 
2.29 (2.08, 2.53) 
2.26 (2.05, 2.49) 
2.25 (2.03, 2.50) 



Lower SES 
1.79 (1.49, 2.16) 
1.53 (1.27, 1.85) 
1.44 (1.19, 1.74) 







Total cholesterol (per 10 mg/dL change) 
1.07 (1.03,1.10) 



HDL cholesterol (per 10 mg/dL change) 
1.02 (0.90,1.14) 



Systolic blood pressure (per 10 mm Hg change) 
1.12 (1.07,1.17) 



Current Smoker 
1.58 (1.05,2.39) 



Antihypertensive medication 
0.79 (0.57,1.09) 



Notes: HR = adjusted hazard ratio; CI = confidence interval; SES = socioeconomic status; HDL = high density lipoprotein. Framingham risk score was complementary log log transformed: log (log (1Framingham risk score)). Model 1 includes SES only; Model 2 includes Framingham risk score only; Model 3 includes both SES and Framingham risk score; Model 4 adds changes in time dependent risk factors. Time dependent risk factors are changes in value of risk factor from baseline (currentbaseline). Blood pressure and lipid change scores were rescaled (by dividing by 10) to produce more interpretable hazard ratios for these measures. 

Franks et al. BMC Cardiovascular Disorders 2011 11:28 doi:10.1186/147122611128 