Table 2

Base case and ranges of efficacy, quality of life, resource use and cost data used (amalgamation of all models)

Base case

Lower, Upper


Effectiveness data

Mean event free years. Values used in sets, not individually for each outcome.

Life years gained

0.010

0.002, same as base case

Myocardial infarction free time gained

0.007

0.008, 0.013

Time free from recurrent angina

0.018

0.014, 0.022

Quality of life data

Values used in sets, not individually for each outcome. Quality of

life change associated with

Death

0.977

same as base case, no upper

myocardial infarction (Q-wave)

0.160

0.102, no upper

Non-Q-wave myocardial infarction

0.088

0.056, no upper

Resource use (per person)

Treatment duration (days)

2.6

2,8

Coronary artery bypass grafting rates at one year

0.014

-0.013,0.041

Angioplasty rates at one year

0.042

0.014, 0.070

Length of stay at 30 days (days)

0.40

-0.50, 0

Myocardial infarction rates at one year (Model 3 only)

0.006

same as base case, 0.013

Recurrence of angina at one year (Model 3 only)

0.017

same as base case, 0.021

Drug treatment costs per person1

Enoxaparin, drug alone per day

£12.16

£9.00, £14.29

Unfractionated heparin loading dose & saline flush

£0.52

£0.41, £0.73

Consumables for loading dose

£0.14

same as base case, £0.16

Unfractionated heparin drawn-up in saline per day

£1.83

£1.37, £2.46

Pump-related costs per day

£1.79

£1.27, £2.54

Monitoring (aPTT tests) per day

£3.67

0, £3.81

Difference in nursing time between enoxaparin and

£3.39

£2.95, £4.36

unfractionated heparin (cost over 2.6 days)

Treatment costs (per person)

(*including length of stay)

Coronary artery bypass grafting*

£6,534

£5,933, £6,952

Angioplasty*

£1,803

£1,647, £2,823

Treatment of acute myocardial infarction* (Model 3 only)

£1,150

£863, £1,385

Treatment of angina* (Model 3 only)

£549

£418, £758

Per in-patient day

£399

£196, same as base case


Notes:1 Upper value includes VAT where appropriate.

Nicholson et al. BMC Cardiovascular Disorders 2001 1:2   doi:10.1186/1471-2261-1-2

Open Data