Table 3

Baseline Characteristics

AOD

No AOD

p


n

27

43

Age (years) (mean [95% CI])

50 [45.0; 55.8]

55 [50.6; 59.2]

0.20

Gender (n men/women)

21/6

15/28

<0.0001

Race (n African American/White/Asian)

20/7/0

22/19/2

0.12

APACHE II (mean [95% CI])

22 [18.2; 25.2]

26 [23.5; 29.0]

0.048

APACHE II excluding GCS (mean [95% CI])

13 [10.6; 17.1]

18 [15.1; 20.2]

0.07

SOFA (mean [95% CI])

8 [6.3; 9.3]

9 [7.5; 9.9]

0.33

Bilirubin* (mg/dl) (mean [95% CI])

2.2 [0.65; 3.85]

1.8 [0.52; 3.07]

0.65

Creatinine (mg/dl) (median, IQR)

1.1 [0.80; 2.20]

1.5 [1.10; 2.80]

0.10

P/F (mean [95% CI])

225 [177.4; 272.8]

218 [181.5; 254.2]

0.81

PEEP (cm H2O) (mean [95% CI])

5 [4.4; 6.4]

5 [3.9; 5.6]

0.30

Reason for mechanical ventilation

0.46

Pneumonia/ALI

4

9

Sepsis

1

4

Delirium/Neurologic

7

10

Asthma/COPD

3

4

Upper airway obstruction

4

3

Hemorrhagic shock

3

4

Cardiac

1

4

Cardiopulmonary arrest

1

2

Drug overdose

3

0

Other

0

3


AOD: alcohol and other drug use disorders

CI: confidence interval

APACHE II: Acute Physiology and Chronic Health Evaluation II

GCS: Glasgow Coma Score

SOFA: Sequential Organ Failure Assessment

*Bilirubin: Total bilirubin measured in 14 patients with AOD and 22 patients without AOD

IQR: Interquartile range

P/F: Partial pressure of oxygen divided by fraction of inspired oxygen

PEEP: Positive end expiratory pressure

de Wit et al. BMC Anesthesiology 2007 7:3   doi:10.1186/1471-2253-7-3

Open Data