BMC Anesthesiology


Open Access Highly Access Research article

Human physiologically based pharmacokinetic model for propofol

David G Levitt1* and Thomas W Schnider2

Author Affiliations

1 Department of Physiology, University of Minnesota, 6–125 Jackson Hall, 321 Church St. S. E., Minneapolis, MN 55455, USA

2 Institut für Anästhesiologie, Kantonspital, CH-9007 Saint Gallen, Switzerland

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BMC Anesthesiology 2005, 5:4 doi:10.1186/1471-2253-5-4

Published: 22 April 2005

Additional files

Additional File 1:

A) A sample Maple worksheet for one subject. This worksheet can be used with the freely available PKQuest program to generate all the data and figures that were used for this subject in this paper. B) A detailed analysis and description of the use of the pharmacokinetics of the volatile anesthetics to determine the lipid fraction in different tissues.

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