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Open Access Highly Accessed Research article

The effect of crystalloid versus medium molecular weight colloid solution on post-operative nausea and vomiting after ambulatory gynecological surgery - a prospective randomized trial

Ivan Hayes, Raza Rathore, Kingsley Enohumah, Edgar Mocanu, Deepak Kumar and Conan McCaul*

BMC Anesthesiology 2012, 12:15  doi:10.1186/1471-2253-12-15

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What about chlorides?

Hans Bahlmann   (2012-12-12 12:09)  University Hospital Link��ping email

An interesting study which helps us a little bit further on the road but it is confusing that the authors mention in the methods section that they used HES in saline (Voluven), while in the discussion they claim that they used "a medium molecular weight starch in a balanced electrolyte solution".
I suppose it was "unbalanced" saline-based Voluven which was used in the study. That would mean that the colloid group received about 60 mmol of chlorides more that the CLS group which could explain the increased incidence of nausea? So three questions remain:
1. Which solution was used
2. If it was Voluven, what do the authors feel about the chloride difference
3. If it was Voluven, why didn't the authors use a real balanced colloid solution such as Volulyte

Competing interests



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