Table 1

Results for oral clearance (OC) models

Model

Task

Kernel

Features

Average test set precision, (+) labels

Average test set precision, (-) labels


OC.1

oral clearance

Gaussian

subset

0.649 (0.060)

0.569 (0.111)

OC.2

oral clearance

linear

subset

0.606 (0.071)*

0.547 (0.107)**

OC.3

oral clearance & bioavailability

Gaussian

subset

0.636 (0.060)

0.625 (0.091)

OC.4

oral clearance & bioavailability

Gaussian

all features

0.626 (0.066)

0.634 (0.108)***

OC.5

oral clearance & bioavailability

linear

subset

0.635 (0.061)

0.637 (0.093)


* Significant differences by ANOVA (p < 0.05): OC.1 vs. OC.2

** Significant differences by ANOVA (p < 0.05): OC.2 vs. OC.3, OC.4, and OC.5 when testing OC.1 through OC.5

*** Significant differences by ANOVA (p < 0.05): OC.4 vs. OC.1 when testing OC.1, OC.3, and OC.4

Boik and Newman BMC Pharmacology 2008 8:12   doi:10.1186/1471-2210-8-12

Open Data