|
24-h urinary chloride (Cl-) excretion data and K+/Cl- ratio in male and female control and NaVPA-rat groups (mean ± SD) |
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| Rat groups |
n |
24-h Cl- level (mmol/l) |
24-h Cl- excretion (mmol/24 h) |
24-h Cl- excretion per 100 g body weight (mmol/100 g) |
Cl-/creatinine ratio |
K+/Cl- ratio |
|
|
||||||
| Control rats |
||||||
| females |
14 |
104 ± 51 |
0.886 ± 0.40 |
0.371 ± 0.15 |
12.6 ± 6.9 |
1.30 ± 0.44 |
| males |
14 |
168 ± 128 |
1.164 ± 0.70 |
0.420 ± 0.26 |
14.2 ± 8.8 |
1.15 ± 0.54 |
| NaVPA-rats |
||||||
| females |
13 |
180 ± 60• |
1.997 ± 0.52• * |
0.833 ± 0.22• * |
24.6 ± 4.7• * |
0.49 ± 0.12• |
| males |
13 |
275 ± 184• |
3.396 ± 1.21• * |
1.208 ± 0.53• * |
34.6 ± 16.5• * |
0.45 ± 0.22• |
|
• – Statistically significant difference, as compared to control group (p < 0.05). * – Statistically significant difference versus the other gender (p < 0.05). | ||||||
Jakutiene et al. BMC Pharmacology 2007 7:9 doi:10.1186/1471-2210-7-9 |
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