Table 2

Effect of CMN on cyclosporine-induced Nitrite levels

Variables
Control
CsA (20)
CMN(15)
CsA (20)+ CMN(5)
CsA (20)+ CMN(10)
CsA (20)+ CMN(15)

Serum Nitrite(μmol/ml)
62 ± 3.72
91.9 ± 50.6a
60 ± 3.15b
77 ± 4.55a,b
69 ± 8.75b
61 ± 3.05b
Tissue nitrite(μmol/mg)
103.518 ± 2.73
190.656 ± 7.97a
101.814 ± 2.27b
174.704 ± 4.01a,b
144.79 ± 3.01a,b
116.912 ± 2.27a,b

Values are expressed mean ± mean. a = Statistical significant at P < 0.05 as compared to control, b = Statistical significant at P < 0.05 as compared to Cyclosporine (CsA)

Tirkey et al. BMC Pharmacology 2005 5:15   doi:10.1186/1471-2210-5-15