Table 1

Effect of Epoxomicin on AA Release from Rat Glial, Human Colon Carcinoma and Human Breast Carcinoma Cells.

Cell Type

% AA Release

MEM/BSA control

With epoxomicin

Rat glial (C-6)

9.0 ± 0.07

11.4 ± 0.28

Human Colon Carcinoma (HT-29)

7.8 ± 0.05

9.4 ± 0.33

Human Breast Carcinoma (BT-20)

12.1 ± 0.35

14.2 ± 0.31

Cells were incubated in the presence and absence of 4.5 μM epoxomicin for 6-h, 12-h or 9-h (C-6, HT-29, BT-20 respectively). Analyses were performed with quadruplicate (C-6 and HT-29) or quintuplicate (BT-20) dishes. All values are expressed as Mean ± SE (n = 4 or n = 5). All data with epoxomicin are statistically significant vs MEM/BSA.

Levine BMC Pharmacology 2004 4:15   doi:10.1186/1471-2210-4-15