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Effect of different concentrations (1, 6 and 12 mM) of kainic acid (KA) on total sulfhydryl groups (TSH) and non-protein sulfhydryl groups (NPSH) following 20 min incubation with rat brain homogenates. |
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| TSH (nmol/mg protein) |
NPSH (μmol/g tissue) |
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|
|
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| Control |
23.97 ± 0.25 |
1.85 ± 0.03 |
| KA (1 mM) |
22.97 ± 0.38 |
1.77 ± 0.05 |
| KA (6 mM) |
20.90 ± 0.27 * |
1.65 ± 0.05 * |
| KA (12 mM) |
19.25 ± 0.35 ** |
1.61 ± 0.04 ** |
|
Values are means ± SEM of 3 experiments. *P < 0.05 and **P < 0.01 with respect to control. | ||
Candelario-Jalil and Sonia León BMC Pharmacology 2003 3:7 doi:10.1186/1471-2210-3-7 |
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