Modulatory action of intravenous general anesthetic at α1β2γ2 GABAA receptors. (a) Single traces of the effects of the intravenous anaesthetics propofol (Prop), etomidate (Etom) and alphaxalone (Alphax) on GABA-evoked chloride currents. (b) The potentiation of the GABA-evoked chloride currents is expressed relative to the control currents at the given GABA concentration (means ± standard error, n = 10–17; *p < 0.05; Student's t-test).
Siegwart et al. BMC Pharmacology 2003 3:13 doi:10.1186/1471-2210-3-13