Figure 5.

Bronchoalveolar lavage levels for myeloperoxidase (MPO) activity, elastase activity and haemoglobin levels in hamsters following the sequential application of LPS and fMLP. Animals were intratracheally challenged with LPS (0.5 mg/kg) or 100 μl of PBS. Twenty four hours after, fMLP (0.25 mg/kg) or 100 μl of vehicle (Veh, 1%DMSO in PBS) was applied intratracheally. Animals were sacrificed two hours after the second challenge and bronchoalveolar lavage performed. Data are expressed as mean ± SEM from 2 different experiments each included 5–10 animals per group. Significance (P < 0.05), indicated by (*) or (#) is versus PBS-challenged/Vehicle-treated hamsters and LPS/Vehicle treated hamsters, respectively.