Table 3

GSH/GSSG Ratio

GSH (μ mol/gm tissue)

GSSG (μ mol/gm tissue)

Ratio


Control

32.12 ± 2.6

11.3 ± 0.71

0.84

CCl4 treated

16.7 ± 1.05

19.6 ± 1.11

-1.14

Natansnin treated

30.03 ± 2.4

11.5 ± 0.85

0.65

Natansnin (10 mg) + CCl4 treated

26.8 ± 1.7

14.7 ± 0.9

-0.16

Natansnin (20 mg) + CCl4 treated

28.1 ± 1.91

14.1 ± 0.81

-0.007


Reduced and oxidized glutathione levels were measured in liver homogenate from control, CCl4 and natansnin (10 mg/kg, 20 mg/kg body weight) treated rats. Glutathione levels are expressed as μmoles per gram tissue. Ratio = GSH-2(GSSG)/GSSG.

Srilaxmi et al. BMC Pharmacology 2010 10:13   doi:10.1186/1471-2210-10-13

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