Main SalB metabolites do not bind MMP-9 CD nor inhibit its activity. (A) No inhibition was found for the two main metabolites of SalB, pyrocatechol and sodium danshensu, on MMP-9 CD activity. (B, C) Biacore analysis for binding of compound with MMP-9. No interaction was found for pyrocatechol (B) or sodium danshensu (C).
Jiang et al. BMC Pharmacology 2010 10:10 doi:10.1186/1471-2210-10-10