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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Andrea Bucceri


Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents. BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.



BMC Featured articles

BMC Pharmacology 2008, 8:11
A metabolite of anxiolytic ocinaplon, DOV 315,090, has a similar pharmacological profile to ocinaplon itself, implying that DOV 315,090 could contribute to the action of ocinaplon but may not be responsible for its non-sedating effects.
Photo: Ablestock.com
BMC Pharmacology 2008, 8:10
Benfotiamine, a non-prescription thiamine precursor indicated for a variety of disorders, has poor lipid solubility and is predicted to have little effect in central nervous system thiamine deficiencies compared with other precursors, despite widespread claims regarding its efficacy.


BMC  Latest articles published in BMC Pharmacology        [more info]


Research article
Alpha-2 adrenergic-induced changes in rectal temperature in adult and 13-day old rats following acute and repeated desipramine administration
Jean D Deupree, William J Burke, David B Bylund
BMC Pharmacology 2008, 8:17 (2October2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.)
Pl A Olsvik, Kai K Lie, Eva Mykkeltvedt, Ole B Samuelsen, Kjell Petersen, Anne-Kristin Stavrum, Bjrn T Lunestad
BMC Pharmacology 2008, 8:16 (11September2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Methoxylation enhances stilbene bioactivity in Caenorhabditis elegans
Mark A Wilson, Agnes M Rimando, Catherine A Wolkow
BMC Pharmacology 2008, 8:15 (13August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats
Rajeshkumar U Koladiya, Amteshwar S Jaggi, Nirmal Singh, Bhupesh K Sharma
BMC Pharmacology 2008, 8:14 (9August2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
A classification model to predict synergism/antagonism of cytotoxic mixtures using protein-drug docking scores
John C Boik, Robert A Newman
BMC Pharmacology 2008, 8:13 (29July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Structure-activity models of oral clearance, cytotoxicity, and LD50: a screen for promising anticancer compounds
John C Boik, Robert A Newman
BMC Pharmacology 2008, 8:12 (13June2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]

Research article
Pharmacological Properties of DOV 315,090, an ocinaplon metabolite
Dmytro Berezhnoy, Maria C Gravielle, Scott Downing, Emmanuel Kostakis, Anthony S Basile, Phil Skolnick, Terrell T Gibbs, David H Farb
BMC Pharmacology 2008, 8:11 (13June2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives
Marie-Laure Volvert, Sandrine Seyen, Marie Piette, Brigitte Evrard, Marjorie Gangolf, Jean-Christophe Plumier, Lucien Bettendorff
BMC Pharmacology 2008, 8:10 (12June2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [1 comment]

Research article
Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells
Jillian G Baker
BMC Pharmacology 2008, 8:9 (6June2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Methodology article
Comparison of four different colorimetric and fluorometric cytotoxicity assays in a zebrafish liver cell line
Stephanie K Bopp, Teresa Lettieri
BMC Pharmacology 2008, 8:8 (30May2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research article
Triphala inhibits both in vitro and in vivo xenograft growth of pancreatic tumor cells by inducing apoptosis
Yan Shi, Ravi P Sahu, Sanjay K Srivastava
BMC Cancer 2008, 8:294 (10October2008)
[Abstract] [Provisional PDF]

Research
Functional identification of NR2 subunits contributing to NMDA receptors on substance P receptor-expressing dorsal horn neurons
Chi-Kun Tong, Edward J Kaftan, Amy B MacDermott
Molecular Pain 2008, 4:44 (10October2008)
[Abstract] [Provisional PDF]

Research article
Delayed internalization and lack of recycling in a beta2-adrenergic receptor fused to the G protein alpha-subunit.
Maria Grazia Di Certo, Enrico M Batassa, Ida Casella, Annalucia Serafino, Aristide Floridi, Claudio Passananti, Paola Molinari, Elisabetta Mattei
BMC Cell Biology 2008, 9:56 (7October2008)
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Case Report
Pancreatic pseudocyst with stent placement in the background of narcotic use: a case report
Stephen Offord, Bora Gumustop, Arthur Shepard
Cases Journal 2008, 1:219 (7October2008)
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Research article
Amphetamine and Pseudoephedrine cross-tolerance measured by c-Fos protein expression in brains of chronically treated rats.
Nootchanart Ruksee, Walaiporn Tongjaroenbuangam, Stefano O Casalotti, Piyarat Govitrapong
BMC Neuroscience 2008, 9:99 (6October2008)
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Case Report
Renal angiomyolipoma presenting with massive retroperitoneal haemorrhage due to deranged clotting factors: a case report
Timothy Wright, Prasanna Sooriakumaran
Cases Journal 2008, 1:213 (4October2008)
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Research article
Rationale for PGI2 in bone marrow edema - from theory to application
Marcus Jager, Frank P Tillmann, Thomas S Thornhill, Marcus Mahmoudi, Dirk Blondin, Gerd R Hetzel, Christoph Zilkens, Rudiger Krauspe
Arthritis Research & Therapy 2008, 10:R120 (3October2008)
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Research
Characterization of mouse orofacial pain and the effects of lesioning TRPV1-expressing neurons on operant behavior
John K. Neubert, Christopher King, Wendi Malphurs, Fong Wong, James P. Weaver, Alan C. Jenkins, Heather L. Rossi, Robert M. Caudle
Molecular Pain 2008, 4:43 (1October2008)
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Research
Ethnomedicinal plant use by Lepcha tribe of Dzongu valley, bordering Khangchendzonga Biosphere Reserve, in North Sikkim, India
Bharat K Pradhan, Hemant K Badola
Journal of Ethnobiology and Ethnomedicine 2008, 4:22 (1October2008)
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Research
Molecular and macromolecular alterations of recombinant adenoviral vectors do not resolve changes in hepatic drug metabolism during infection
Shellie M Callahan, Piyanuch Wonganan, Maria A Croyle
Virology Journal 2008, 5:111 (30September2008)
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