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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Danielle Burgess PhD
Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents.
BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus and Google Scholar.
BMC Pharmacology 2009, 9 :12
A drug delivery vehicle that uses the non-toxic heavy chain of botulinum neurotoxin-A to gain entry to neurons via endocytosis could rescue synapses poisoned by botox, once an effective antidote is found.
BMC Pharmacology 2009, 9 :10
Amphiphilic psychotropic drugs stimulate cellular lipid biosynthesis and concomitantly upregulate mRNA levels of key genes in reverse cholesterol transport and lipid efflux in cultured human central nervous system and liver cells.
Volume 9 Suppl 2
Meeting abstracts
Graz, Austria. 19-21 November 2009
Volume 9 Suppl 1
Meeting abstracts
Regensburg, Germany. 19
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Research article
An efficient drug delivery vehicle for botulism countermeasure Peng Zhang, Radharaman Ray, Bal Ram Singh, Dan Li, Michael Adler, Prabhati Ray BMC Pharmacology 2009, 9 :12 (27 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Evaluation of molecular descriptors for antitumor drugs with respect to noncovalent binding to DNA and antiproliferative activity Jos BMC Pharmacology 2009, 9 :11 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells Audun O Vik-Mo, Johan Fern BMC Pharmacology 2009, 9 :10 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen Rebecca A Roof, David L Roman, Samuel T Clements, Katarzyna Sobczyk-Kojiro, Levi L Blazer, Shodai Ota, Henry I Mosberg, Richard R Neubig BMC Pharmacology 2009, 9 :9 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models Nancy Lee, Chelsey L Woodrum, Alison M Nobil, Aubrey E Rauktys, Michael P Messina, Sandra L Dabora BMC Pharmacology 2009, 9 :8 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes Rong Shi, Chuan-Chin Huang, Robert S Aronstam, Nuran Ercal, Adam Martin, Yue-Wern Huang BMC Pharmacology 2009, 9 :7 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Haloperidol changes mRNA expression of a QKI splice variant in human astrocytoma cells Lin Jiang, Peter Saetre, Elena Jazin, Eva Lindholm Carlstr BMC Pharmacology 2009, 9 :6 (31 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Preferential uptake of the non steroid anti-inflammatory drug diclofenac into inflamed tissues after a single oral dose in rats A Schweitzer, N Hasler-Nguyen, J Zijlstra BMC Pharmacology 2009, 9 :5 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Bioinformatic characterizations and prediction of K+ and Na+ ion channels effector toxins Rima Soli, Belhassen Kaabi, Mourad Barhoumi, Mohamed El-Ayeb, Najet Srairi-Abid BMC Pharmacology 2009, 9 :4 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The mode of action of dimeticone 4% lotion against head lice, Pediculus capitis Ian F Burgess BMC Pharmacology 2009, 9 :3 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Infliximab concentration monitoring improves the control of disease activity in rheumatoid arthritis Denis Mulleman, Jean-Camille Meric, Gilles Paintaud, Emilie Ducourau, Charlotte Magdelaine-Beuzelin, Jean-Pierre Valat, Philippe Goupille Arthritis Research & Therapy 2009, 11 :R178 (25 [Abstract ] [Provisional PDF ]
Research
Attenuation by dextromethorphan on the higher liability to morphine-induced reward, caused by prenatal exposure of morphine in rat offspring Ling-Yi Wu, Jain-Fang Chen, Pao-Luh Tao, Eagle Yi-Kung Huang Journal of Biomedical Science 2009, 16 :106 (25 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production Maurizio Cutolo, Stefano Soldano, Paola Montagna, Alberto Sulli, Bruno Seriolo, Barbara Villaggio, Pierfranco Triolo, Paolo Clerico, Lamberto Felli, Renata Brizzolara Arthritis Research & Therapy 2009, 11 :R176 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Developmental expression of a functional TASK-1 2P domain K+ channel in embryonic chick heart Hengtao Zhang, Jeremy Parker, Neal Shepherd, Tony L Creazzo Journal of Biomedical Science 2009, 16 :104 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Short report
Treatment of hypertriglyceridemia and HIV: fenofibrate-induced changes in the expression of chemokine genes in circulating leukocytes Carlos Alonso-Villaverde, Gerard Aragon AIDS Research and Therapy 2009, 6 :26 (23 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research
Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver Eliete JB Bighetti, Patr Lipids in Health and Disease 2009, 8 :50 (23 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Studies on the antidiarrhoeal activity of Aegle marmelos unripe fruit: Validating its traditional usage Brijesh S, Poonam Daswani, Pundarikakshudu Tetali, Noshir Antia, Tannaz Birdi BMC Complementary and Alternative Medicine 2009, 9 :47 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
The effects of corn silk on glycaemic metabolism Jianyou Guo, Tongjun Liu, Linna Han, Yongmei Liu Nutrition & Metabolism 2009, 6 :47 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Case Report
Fluconazole induced toxic epidermal necrolysis: a case report Uchenna R Ofoma, Edward K Chapnick Cases Journal 2009, 2 :9071 (20 [Abstract ] [Full Text ] [PDF ]
Research article
Topical recombinant thrombin at a concentration of 1000 IU/mL reliably shortens in vivo TTH and delivers durable hemostasis in the presence of heparin anticoagulation and clopidogrel platelet inhibition in a rabbit model of vascular bleeding Steven D Hughes, Paul D Bishop, Richard Garcia, Tracy Zhang, W. Allan Alexander Annals of Surgical Innovation and Research 2009, 3 :14 (19 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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