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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Scott Edmunds, PhD
Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents.
BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.
BMC Pharmacology 2009, 9 :6
Human astrocytoma cells treated with the antipsychotic drug haloperidol show increased mRNA expression of QK1, a gene previously identified as a candidate gene for schizophrenia.
BMC Pharmacology 2009, 9 :3
Treatment with dimeticone blocks the spiracles of headlice but does not cause instant asphyxiation - instead the lice die slowly as water loss through the spiracles is impeded, causing physiological stress and occasionally osmotic rupture of the gut.
Washington, DC, USA. 2-3 February 2009 BMC Neurology 2009,
9 (Suppl 1)
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Research article
A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen Rebecca A Roof, David L Roman, Samuel T Clements, Katarzyna Sobczyk-Kojiro, Levi L Blazer, Shodai Ota, Henry I Mosberg, Richard R Neubig BMC Pharmacology 2009, 9 :9 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models Nancy Lee, Chelsey L Woodrum, Alison M Nobil, Aubrey E Rauktys, Michael P Messina, Sandra L Dabora BMC Pharmacology 2009, 9 :8 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes Rong Shi, Chuan-Chin Huang, Robert S Aronstam, Nuran Ercal, Adam Martin, Yue-Wern Huang BMC Pharmacology 2009, 9 :7 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Haloperidol changes mRNA expression of a QKI splice variant in human astrocytoma cells Lin Jiang, Peter Saetre, Elena Jazin, Eva Lindholm Carlstr BMC Pharmacology 2009, 9 :6 (31 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Preferential uptake of the non steroid anti-inflammatory drug diclofenac into inflamed tissues after a single oral dose in rats A Schweitzer, N Hasler-Nguyen, J Zijlstra BMC Pharmacology 2009, 9 :5 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Bioinformatic characterizations and prediction of K+ and Na+ ion channels effector toxins Rima Soli, Belhassen Kaabi, Mourad Barhoumi, Mohamed El-Ayeb, Najet Srairi-Abid BMC Pharmacology 2009, 9 :4 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The mode of action of dimeticone 4% lotion against head lice, Pediculus capitis Ian F Burgess BMC Pharmacology 2009, 9 :3 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
AICAR activates the pluripotency transcriptional network in embryonic stem cells and induces KLF4 and KLF2 expression in fibroblasts Luigi Adamo, Yuzhi Zhang, Guillermo Garc BMC Pharmacology 2009, 9 :2 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Conformational changes in James T McLaughlin, Sean C Barron, Jennifer A See, Robert L Rosenberg BMC Pharmacology 2009, 9 :1 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000 Zhan-Guo Gao, Kai Ye, Anik BMC Pharmacology 2008, 8 :20 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Letter
10% Hydroxyethylstarch impairs renal function and induces interstitial proliferation, macrophage infiltration and tubular damage Martin Siegemund Critical Care 2009, 13 :413 (8 [PDF ]
Research
Activation of estrogen receptor beta-dependent nitric oxide signaling mediates the hypotensive effects of estrogen in the rostral ventrolateral medulla of anesthetized rats Cheng-Dean Shih Journal of Biomedical Science 2009, 16 :60 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Anti-malarial activity of 6-(8' Z-pentadecenyl)-salicylic acid from Viola websteri in mice Ill-Min Chung, Su-Hyun Seo, Eun-Young Kang, Won-Hwan Park, Hyung-in Moon Malaria Journal 2009, 8 :151 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Short report
Trypanocidal activity of the proteasome inhibitor and anti-cancer drug bortezomib Dietmar Steverding, Xia Wang Parasites & Vectors 2009, 2 :29 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Disagreements with implications: Diverging discourses on the ethics of non-medical use of methylphenidate for performance enhancement Cynthia Forlini, Eric Racine BMC Medical Ethics 2009, 10 :9 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Assessment of the medicinal potentials of the methanol extracts of the leaves and stems of Buddleja saligna. Adeolu A Adedapo, Florence O Jimoh, Srinivas Vedic, Patrick J Masika, Anthony J Afolayan BMC Complementary and Alternative Medicine 2009, 9 :21 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Role of ERK/MAPK in endothelin receptor signaling in human aortic smooth muscle cells Qing-Wen Chen, Lars Edvinsson, Cang-Bao Xu BMC Cell Biology 2009, 10 :52 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Effects of triptolide from Radix Tripterygium wilfordii (Leigongteng) on cartilage cytokines and transcription factor NF-kappaB: a study on induced arthritis in rats Cheng Xiao, Jing Zhou, Yinghui He, Hongwei Jia, Linhua Zhao, Ning Zhao, Aiping Lu Chinese Medicine 2009, 4 :13 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes Haijun Zhang, Wenjun Xin, Patrick M Dougherty Molecular Pain 2009, 5 :36 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain Leonardo Guasti, Denise Richardson, Maulik Jhaveri, Khalil Eldeeb, David A Barrett, Maurice R Elphick, Stephen PH Alexander, David A Kendall, Gregory J Michael, Victoria Chapman Molecular Pain 2009, 5 :35 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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