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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Andrea Bucceri
Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents.
BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.
BMC Pharmacology 2008, 8 :11
A metabolite of anxiolytic ocinaplon, DOV 315,090, has a similar pharmacological profile to ocinaplon itself, implying that DOV 315,090 could contribute to the action of ocinaplon but may not be responsible for its non-sedating effects.
BMC Pharmacology 2008, 8 :10
Benfotiamine, a non-prescription thiamine precursor indicated for a variety of disorders, has poor lipid solubility and is predicted to have little effect in central nervous system thiamine deficiencies compared with other precursors, despite widespread claims regarding its efficacy.
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Research article
Alpha-2 adrenergic-induced changes in rectal temperature in adult and 13-day old rats following acute and repeated desipramine administration Jean D Deupree, William J Burke, David B Bylund BMC Pharmacology 2008, 8 :17 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.) P BMC Pharmacology 2008, 8 :16 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Methoxylation enhances stilbene bioactivity in Caenorhabditis elegans Mark A Wilson, Agnes M Rimando, Catherine A Wolkow BMC Pharmacology 2008, 8 :15 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats Rajeshkumar U Koladiya, Amteshwar S Jaggi, Nirmal Singh, Bhupesh K Sharma BMC Pharmacology 2008, 8 :14 (9 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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A classification model to predict synergism/antagonism of cytotoxic mixtures using protein-drug docking scores John C Boik, Robert A Newman BMC Pharmacology 2008, 8 :13 (29 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Structure-activity models of oral clearance, cytotoxicity, and LD50: a screen for promising anticancer compounds John C Boik, Robert A Newman BMC Pharmacology 2008, 8 :12 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [Cited on BioMed Central ]
Research article
Pharmacological Properties of DOV 315,090, an ocinaplon metabolite Dmytro Berezhnoy, Maria C Gravielle, Scott Downing, Emmanuel Kostakis, Anthony S Basile, Phil Skolnick, Terrell T Gibbs, David H Farb BMC Pharmacology 2008, 8 :11 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives Marie-Laure Volvert, Sandrine Seyen, Marie Piette, Brigitte Evrard, Marjorie Gangolf, Jean-Christophe Plumier, Lucien Bettendorff BMC Pharmacology 2008, 8 :10 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ] [1 comment ]
Research article
Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells Jillian G Baker BMC Pharmacology 2008, 8 :9 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Comparison of four different colorimetric and fluorometric cytotoxicity assays in a zebrafish liver cell line Stephanie K Bopp, Teresa Lettieri BMC Pharmacology 2008, 8 :8 (30 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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Triphala inhibits both in vitro and in vivo xenograft growth of pancreatic tumor cells by inducing apoptosis Yan Shi, Ravi P Sahu, Sanjay K Srivastava BMC Cancer 2008, 8 :294 (10 [Abstract ] [Provisional PDF ]
Research
Functional identification of NR2 subunits contributing to NMDA receptors on substance P receptor-expressing dorsal horn neurons Chi-Kun Tong, Edward J Kaftan, Amy B MacDermott Molecular Pain 2008, 4 :44 (10 [Abstract ] [Provisional PDF ]
Research article
Delayed internalization and lack of recycling in a beta2-adrenergic receptor fused to the G protein alpha-subunit. Maria Grazia Di Certo, Enrico M Batassa, Ida Casella, Annalucia Serafino, Aristide Floridi, Claudio Passananti, Paola Molinari, Elisabetta Mattei BMC Cell Biology 2008, 9 :56 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Case Report
Pancreatic pseudocyst with stent placement in the background of narcotic use: a case report Stephen Offord, Bora Gumustop, Arthur Shepard Cases Journal 2008, 1 :219 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Amphetamine and Pseudoephedrine cross-tolerance measured by c-Fos protein expression in brains of chronically treated rats. Nootchanart Ruksee, Walaiporn Tongjaroenbuangam, Stefano O Casalotti, Piyarat Govitrapong BMC Neuroscience 2008, 9 :99 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Case Report
Renal angiomyolipoma presenting with massive retroperitoneal haemorrhage due to deranged clotting factors: a case report Timothy Wright, Prasanna Sooriakumaran Cases Journal 2008, 1 :213 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Rationale for PGI2 in bone marrow edema - from theory to application
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Characterization of mouse orofacial pain and the effects of lesioning TRPV1-expressing neurons on operant behavior John K. Neubert, Christopher King, Wendi Malphurs, Fong Wong, James P. Weaver, Alan C. Jenkins, Heather L. Rossi, Robert M. Caudle Molecular Pain 2008, 4 :43 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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Ethnomedicinal plant use by Lepcha tribe of Dzongu valley, bordering Khangchendzonga Biosphere Reserve, in North Sikkim, India
Bharat K Pradhan, Hemant K Badola Journal of Ethnobiology and Ethnomedicine 2008, 4 :22 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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Molecular and macromolecular alterations of recombinant adenoviral vectors do not resolve changes in hepatic drug metabolism during infection Shellie M Callahan, Piyanuch Wonganan, Maria A Croyle Virology Journal 2008, 5 :111 (30 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
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