Figure 1.

Selective amyloid-β lowering agents that do not affect Notch processing. Tarenflurbil and 1367 work in purified γ-secretase assays, whereas LDDN-9918 was identified from a cell-based screen and works through an unknown mechanism.

Wolfe BMC Neuroscience 2008 9(Suppl 2):S4   doi:10.1186/1471-2202-9-S2-S4