Figure 4.

Schematic representation of physiological iron homeostasis mechanisms, including Aβ generation as a compensatory process that reduces OS damage and the pathological mechanisms of iron-induced neurodegeneration in AD and its prevention by iron chelators.

Avramovich-Tirosh et al. BMC Neuroscience 2008 9(Suppl 2):S2   doi:10.1186/1471-2202-9-S2-S2