Research article
Changes in corticospinal excitability and the direction of evoked movements during motor preparation: A TMS study
BMC Neuroscience 2008, 9:51 doi:10.1186/1471-2202-9-51
Research article
Research article
BMC Neuroscience 2008, 9:51 doi:10.1186/1471-2202-9-51
The modulation of corticospinal excitability during the foreperiod
Craig Sinclair (2008-07-28 12:07) University of Western Australia
I was interested by your findings presented in this paper.
I found the observation of a significant Precue x Time interaction in the prime mover APB muscle to be interesting. In particular, the fact that the MEP amplitude appeared to decline across the foreperiod when the precued movement was one which maximally engaged the APB muscle (180, 225, or 270 degrees movements) as opposed to when the precued movement was not requiring such strong abduction/flexion (90, 135 degrees movements).
I wonder if this might reflect a movement specific suppression of MEP amplitude in the prime mover muscle during the foreperiod? If so, do you think that this might involve a different inhibitory mechanism to the more generalized suppression seen in the non-involved FDI muscle regardless of the precued direction?
Competing interests
No competing interests
top